Evidence map›Paper›PMID 31351469›Full record

ArticleBMC geriatrics2019

Associations between prevalent multimorbidity combinations and prospective disability and self-rated health among older adults in Europe.

Paige E Sheridan, Christine A Mair, Ana R Quiñones

Abstract read
In one paragraph

Article in BMC geriatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  5. Optimising Investment in Health Innovations in Europe.Journal of market access & health policy · 2026
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  18. Multimorbidity patterns and health-related quality of life among community-dwelling older adults: evidence from a rural town in Suzhou, China.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
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2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Paige E SheridanDepartment of Family Medicine and Public Health, University of California, San Diego School of Medicine, San Diego, California, USA.
Christine A MairDepartment of Sociology & Anthropology, University of Maryland, Baltimore County, Baltimore, MD, USA.
Ana R QuiñonesDepartment of Family Medicine and OHSU-PSU School of Public Health, Oregon Health & Science University, Portland, Oregon, USA. quinones@ohsu.edu.ORCID 0000-0001-6554-7734

Funding

Changes in Multimorbidity and Disability Among Race/Ethnic Older Adults (Administrative Supplement)R01AG055681 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI QUINONES, ANA ROMAN · 2017 to 2021
$2.8M
NIA NIH HHS R01 AG055681
6 · The paper itself

Abstract

backgroundMultimorbidity is associated with greater likelihood of disability, health-related quality of life, and mortality, greater than the risk attributable to individual diseases. The objective of this study is to examine the association between unique multimorbidity combinations and prospective disability and poor self-rated health (SRH) in older adults in Europe.

methodsWe conducted a prospective analysis using data from the Survey of Health, Ageing and Retirement in Europe in 2013 and 2015. We used hierarchical models to compare respondents with multiple chronic conditions to healthy respondents and respondents reporting only one chronic condition and made within-group comparisons to examine the marginal contribution of specific chronic condition combinations.

resultsLess than 20% of the study population reported having zero chronic conditions, while 50% reported having at least two chronic conditions. We identified 380 unique disease combinations among people who reported having at least two chronic conditions. Over 35% of multimorbidity could be attributed to five specific multimorbidity combinations, and over 50% to ten specific combinations. Overall, multimorbidity combinations that included high depressive symptoms were associated with increased odds of reporting poor SRH, and increased rates of ADL-IADL disability.

conclusionsMultimorbidity groups that include high depressive symptoms may be more disabling than combinations that include only somatic conditions. These findings argue for a continued integration of both mental and somatic chronic conditions in the conceptualization of multimorbidity, with important implications for clinical practice and healthcare delivery.

Indexed as

Health StatusSelf ReportAgedAged, 80 and overAgingChronic DiseaseEuropeFemaleHumansLongitudinal StudiesMaleMiddle AgedMultimorbidityPersons with DisabilitiesPrevalenceProspective StudiesDepressionDisabilityMultimorbidityMultiple chronic conditionsSelf-rated health

Identifiers

PMID31351469
PMCPMC6661084

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.