Evidence map›Paper›PMID 31351463›Full record

ArticleBMC public health2019

Adverse childhood events and risk of diabetes onset in the 1979 National longitudinal survey of youth cohort.

E Anne Lown, Camillia K Lui, Kate Karriker-Jaffe, Nina Mulia, Edwina Williams, Yu Ye, Libo Li, Thomas K Greenfield, William C Kerr

Open access · goldAbstract read
In one paragraph

Article in BMC public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
8.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Parent-Child Interaction Therapy Supports Healthy Eating Behavior in Child Welfare-Involved Children.International journal of environmental research and public health · 2022
    Trial
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  9. The nature and nurture of resilience-reactions of trizygotic triplet minors to their father's death.Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater · 2023
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  15. Experiencing Household Food Insecurity During Adolescence Predicts Disordered Eating and Elevated Body Mass Index 8 Years Later.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

E Anne LownDepartment of Social and Behavioral Sciences, School of Nursing, University of California, 3333 California Street, San Francisco, CA, 94118, USA. Anne.Lown@ucsf.edu.ORCID http://orcid.org/0000-0002-7502-4459
Camillia K LuiAlcohol Research Group, Public Health Institute, 6001 Shellmound Ave, Suite 450, Emeryville, CA, 94608, USA.
Kate Karriker-JaffeAlcohol Research Group, Public Health Institute, 6001 Shellmound Ave, Suite 450, Emeryville, CA, 94608, USA.
Nina MuliaAlcohol Research Group, Public Health Institute, 6001 Shellmound Ave, Suite 450, Emeryville, CA, 94608, USA.
Edwina WilliamsAlcohol Research Group, Public Health Institute, 6001 Shellmound Ave, Suite 450, Emeryville, CA, 94608, USA.
Yu YeAlcohol Research Group, Public Health Institute, 6001 Shellmound Ave, Suite 450, Emeryville, CA, 94608, USA.
Libo LiAlcohol Research Group, Public Health Institute, 6001 Shellmound Ave, Suite 450, Emeryville, CA, 94608, USA.
Thomas K GreenfieldAlcohol Research Group, Public Health Institute, 6001 Shellmound Ave, Suite 450, Emeryville, CA, 94608, USA.
William C KerrAlcohol Research Group, Public Health Institute, 6001 Shellmound Ave, Suite 450, Emeryville, CA, 94608, USA.
Public Health Institute · USUniversity of California, San Francisco · US

Funding

Inter-Relationships Between Life-Course Alcohol Patterns and Health ConditionsR01AA021448 · NIAAA · PUBLIC HEALTH INSTITUTE · PI KERR, WILLIAM C. · 2014 to 2017
$1.6M
National Institute on Alcohol Abuse and Alcoholism R01AA021448NIAAA NIH HHS R01 AA021448
6 · The paper itself

Abstract

backgroundType 2 diabetes is a major public health problem with considerable personal and societal costs. Adverse childhood experiences (ACE) are associated with a number of serious and chronic health problems in adulthood, but these experiences have not been adequately studied in relation to diabetes in a US national sample. The association between ACE and poor health can be partially explained by greater risky health behaviors (RHB) such as smoking, heavy alcohol use, or obesity. Few studies have examined ACE in relation to adult onset Type 2 diabetes mellitus (T2DM) taking into account the role of RHB. Using longitudinal data from a representative US population sample followed over 30 years, this study examines the impact of ACE on the risk of diabetes onset.

methodsData from the 1982 to 2012 waves of the 1979 National Longitudinal Survey of Youth were analyzed, spanning ages 14 to 56. Bivariate and discrete-time survival models were used to assess the relationships between ACE and RHB including smoking, alcohol use, and obesity, and subsequent onset of diabetes.

resultsT2DM was reported by almost 10% of participants. Over 30% of women and 21% of men reported 2+ ACE events. Women reporting 2-3 or 4+ ACE events were more likely to develop diabetes with the mean number of ACE events being greater in those with diabetes compared to without (1.28 vs.1.05, p < .0001). For men there was no significant association between ACE and diabetes onset. For women, ACE was associated with heavy drinking, current smoking, and obesity. For men, ACE was associated with being underweight and daily smoking. In multivariate discrete-time survival models, each additional ACE increased risk of T2DM onset (OR

conclusionACE predicted diabetes onset among women, though this relationship was attenuated when controlling for BMI. Being overweight or obese was significantly more common among women with a history of ACE, which suggests BMI may be on the pathway from ACE to diabetes onset for women.

Indexed as

AdolescentAdultAdverse Childhood ExperiencesAlcohol DrinkingDiabetes Mellitus, Type 2FemaleHealth Risk BehaviorsHumansLongitudinal StudiesMaleMiddle AgedObesityRisk FactorsSmokingUnited StatesYoung AdultAdverse childhood eventsAlcoholBody mass indexObesityTobaccoType 2 diabetes mellitus

Identifiers

PMID31351463
PMCPMC6661082
OpenAlexW2965804612

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.