ArticleScientific reports2019
Salpingitis Impairs Bovine Tubal Function and Sperm-Oviduct Interaction.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Expression ofInternational journal of molecular sciences · 2023Pooled it
- Multi-omics profiling identifies inosine as a key metabolite associated with embryonic arrest in hydrosalpinx-associated infertility.EBioMedicine · 2026Article
- Tubal Patency Decoction and Its Ingredient β-Sitosterol Alleviate Tubal Infertility by Inhibiting Inflammation and Promoting Cilia Formation Through PGR.Mediators of inflammation · 2026Article
- [Evaluation ofZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025Article
- Evaluation of tubal patency with hysterosalpingo-contrast sonography using sodium alginate solution and the subsequent fertility outcomes in repeat breeder cattle.The Journal of reproduction and development · 2025Article
- Age, lifestyle, and disease affect ciliary transport in the human fallopian tube.Scientific reports · 2025Article
- Examining the prevalence of reproductive tract infections (RTIs) and their correlation with knowledge, attitudes, and practices (KAP): a cross-sectional study among university-affiliated women.BMC public health · 2025Article
- Review
- Sperm in the Mammalian Female Reproductive Tract: Surfing Through the Tract to Try to Beat the Odds.Annual review of animal biosciences · 2024Review
- In vivo dynamics of pro-inflammatory factors, mucins, and polymorph nuclear neutrophils in the bovine oviduct during the follicular and luteal phase.Scientific reports · 2023Article
- Protective Effect of Clostridium butyricum on Escherichia coli-Induced Endometritis in Mice via Ameliorating Endometrial Barrier and Inhibiting Inflammatory Response.Microbiology spectrum · 2022Article
- Clinical, laboratory, and morphological diagnosis of diseases in the oviducts and paraovarian structures of cows.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2022Article
- Sperm-oviduct interactions: Key factors for sperm survival and maintenance of sperm fertilizing capacity.Andrology · 2022Review
- Mechanistic Drivers of Müllerian Duct Development and Differentiation Into the Oviduct.Frontiers in cell and developmental biology · 2021Review
- Bovine sperm-oviduct interactions are characterized by specific sperm behaviour, ultrastructure and tubal reactions which are impacted by sex sorting.Scientific reports · 2020Article
- Clinical and structural changes in reproductive organs and endocrine glands of sterile cows.Veterinary world · 2019Article
- Enhancing female fertility by biomaterial-based regeneration of uterine tubes.Cell transplantationReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Salpingitis is a common cause for subfertility and infertility both in humans and animals. However, the effects of salpingitis on tubal function and reproductive success are largely unknown. Therefore we set out to investigate the effects of inflammation on sperm and oocyte transport and gameto-maternal interaction in the oviduct using the bovine as a model. For this purpose, oviducts revealing mild (n = 45), moderate (n = 55) and severe (n = 45) inflammation were obtained from cows immediately after slaughter and investigated by live cell imaging, histochemistry and scanning electron microscopy. Our studies showed that endometritis was always correlated with salpingitis. Moderate and severe inflammation caused a significant increase in the thickness of tubal folds (p < 0.05). Severe inflammation was characterized by luminal accumulations of mucus and glycoproteins, increased apoptosis, loss of tight junctions and shedding of tubal epithelial cells. The mean ciliary beat frequency (CBF) in the ampulla was significantly reduced as compared to the controls (p < 0.05). The higher the grade of inflammation, the lower was the CBF (p < 0.001). In severe inflammation, spermatozoa were stuck in mucus resulting in decreased sperm motility. Our results imply that tubal inflammation impairs proper tubal function and leads to reduced sperm fertilizing capacity.
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Registered trials
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