Evidence map›Paper›PMID 31350450›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2019

Trends in reticulocyte hemoglobin equivalent values in critically ill neonates, stratified by gestational age.

Kendell German, Phuong T Vu, Jill D Irvine, Sandra E Juul

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. A CBC drawn postnatally from umbilical cord blood can provide valuable diagnostic information for infants admitted to the NICU.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Review
  3. Review
  4. Serum ferritin values in neonates <29 weeks' gestation are highly variable and do not correlate with reticulocyte hemoglobin content.Journal of perinatology : official journal of the California Perinatal Association · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Urinary ferritin; a potential noninvasive way to screen NICU patients for iron deficiency.Journal of perinatology : official journal of the California Perinatal Association · 2021
    Article
  11. Reconciling markedly discordant values of serum ferritin versus reticulocyte hemoglobin content.Journal of perinatology : official journal of the California Perinatal Association · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kendell GermanDivision of Neonatology, University of Washington/Seattle Children's Hospital, Seattle, WA, USA. germank@uw.edu.
Phuong T VuDepartment of Biostatistics, University of Washington, Seattle, WA, USA.
Jill D IrvineDepartment of Nutrition Therapy, University of Washington, Seattle, WA, USA.
Sandra E JuulDivision of Neonatology, University of Washington/Seattle Children's Hospital, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-6861-6229

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe reticulocyte index reticulocyte hemoglobin equivalent (Ret-He) was evaluated as a marker of iron status. STUDY

designThis is a retrospective cohort study of all infants admitted to the University of Washington Neonatal Intensive Care Unit, who received Ret-He measurements as part of routine care within the first 120 days of life.

resultA total of 730 Ret-He measurements from 249 infants were analyzed (median gestational age at birth 32.1 weeks; 49 infants <28 weeks and 200 ≥28 weeks). Initial Ret-He measurements were lower in infants <28 weeks (28.24 vs. 33.34 pg). Ret-He values initially decreased, then slowly increased. Infants received an average of 3.9, 6.5, and 8.2 mg/kg/day of enteral iron sulfate at 30, 60, and 90 days, respectively.

conclusionRet-He values showed a slow uptrend with enteral iron supplementation following an initial decrease, suggesting that neonates are able to improve their iron sufficiency status with supplementation.

Indexed as

Critical IllnessIron DeficienciesReticulocytesAnemia, Iron-DeficiencyBiomarkersDietary SupplementsErythrocyte CountGestational AgeHemoglobinsHumansInfant, NewbornInfant, PrematureInfant, Premature, DiseasesIntensive Care Units, NeonatalIronRetrospective StudiesBiomarkersHemoglobinsIron

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.