ArticleScientific reports2019
A non-enzymatic glucose sensor enabled by bioelectronic pH control.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed.
- Metal-organic framework-based wearable electrochemical glucose sensors for sweat analysis: materials design, sensing mechanisms, and future perspectives.RSC advances · 2026Review
- Seamless human electronics interfacing through advanced skin attachable and implantable sensor technologies.Discover nano · 2026Review
- Can nanozymes achieve more than enzymes?Nature reviews. Materials · 2026Article
- Smart Antidiabetic Nanomedicine: A Revolutionized Therapeutic Approach for Treatment of Diabetes Mellitus.Bioengineering (Basel, Switzerland) · 2025Review
- Engineered single chain variable fragments (scFvs) with improved pH-dependent kinetics for use in continuous biosensor applications.RSC advances · 2025Article
- Advances in 2D materials for wearable biomonitoring.Materials science & engineering. R, Reports : a review journal · 2025Article
- Laser-generated Pt/Ni nanocatalysts-carbon nanofibers enabling self-calibrated enzyme-free glucose detection at physiological pH.Analytical and bioanalytical chemistry · 2025Article
- New cobalt hydroxycarbonate-based material for highly sensitive enzyme-free glucose sensors.Scientific reports · 2025Article
- A Facile Method for Synthesizing Cobalt Oxide Nanoparticles to Create a Highly Sensitive Non-Enzyme Glucose Sensor.Biosensors · 2025Article
- Control of sensitivity in metal oxide electrolyte gated field-effect transistor-based glucose sensor by electronegativity modulation.Scientific reports · 2024Article
- LIG-Based High-Sensitivity Multiplexed Sensing System for Simultaneous Monitoring of Metabolites and Electrolytes.Sensors (Basel, Switzerland) · 2024Article
- Recent Development on Sensing Strategies for Small Molecules Detections.Journal of fluorescence · 2024Review
- Optimized Copper-Based Microfeathers for Glucose Detection.Biosensors · 2023Article
- Recent Advances in Metal-Organic Frameworks (MOFs) and Their Composites for Non-Enzymatic Electrochemical Glucose Sensors.Bioengineering (Basel, Switzerland) · 2023Review
- Multifunctional Biosensing Platform Based on Nickel-Modified Laser-Induced Graphene.Bioengineering (Basel, Switzerland) · 2023Article
- Progress of Enzymatic and Non-Enzymatic Electrochemical Glucose Biosensor Based on Nanomaterial-Modified Electrode.Biosensors · 2022Review
- CuO Nanowires Fabricated by Thermal Oxidation of Cu Foils towards Electrochemical Detection of Glucose.Micromachines · 2022Article
- Upcycling Compact Discs for Flexible and Stretchable Bioelectronic Applications.Nature communications · 2022Article
- Development of GO/Co/Chitosan-Based Nano-Biosensor for Real-Time Detection of D-Glucose.Biosensors · 2022Article
- A dual-functional flexible sensor based on defects-free Co-doped ZnO nanorods decorated with CoO clusters towards pH and glucose monitoring of fruit juices and human fluids.Nano convergence · 2022Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Continuous glucose monitoring from sweat and tears can improve the quality of life of diabetic patients and provide data for more accurate diagnosis and treatment. Current continuous glucose sensors use enzymes with a one-to-two week lifespan, which forces periodic replacement. Metal oxide sensors are an alternative to enzymatic sensors with a longer lifetime. However, metal oxide sensors do not operate in sweat and tears because they function at high pH (pH > 10), and sweat and tears are neutral (pH = 7). Here, we introduce a non-enzymatic metal oxide glucose sensor that functions in neutral fluids by electronically inducing a reversible and localized pH change. We demonstrate glucose monitoring at physiologically relevant levels in neutral fluids mimicking sweat, and wireless communication with a personal computer via an integrated circuit board.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.