ArticleScientific reports2019
Early-life factors are associated with waist circumference and type 2 diabetes among Ghanaian adults: The RODAM Study.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed, 26 citations in OpenAlex.
- Prevention of type 2 diabetes in migrant populations from low- and middle-income countries living in high-income countries.Diabetologia · 2025Review
- Cardiovascular Disease Burden among African Migrants.Current atherosclerosis reports · 2025Review
- Review of Current Strategies to Address Micronutrient Deficiencies (MNDs) in Ghana: A Scoping Review.Journal of nutrition and metabolism · 2025Review
- Contextual awareness, response and evaluation (CARE) of diabetes in poor urban communities in Ghana: the CARE diabetes project qualitative study protocol.Global health action · 2024Article
- Subgroups of adult-onset diabetes: a data-driven cluster analysis in a Ghanaian population.Scientific reports · 2023Article
- Pathophysiology of type 2 diabetes in sub-Saharan Africans.Diabetologia · 2022Review
- The Magnitude and Directions of the Associations between Early Life Factors and Metabolic Syndrome Differ across Geographical Locations among Migrant and Non-Migrant Ghanaians-The RODAM Study.International journal of environmental research and public health · 2021Article
- Estimating trunk fat in children according to sex using basic somatic readings: an opportunity for improving evaluation among girls.BMC pediatrics · 2021Article
- Evolutionary forces in diabetes and hypertension pathogenesis in Africans.Human molecular genetics · 2021Review
- Current Pharmacological Treatment of Type 2 Diabetes Mellitus in Undocumented Migrants: Is It Appropriate for the Phenotype of the Disease?International journal of environmental research and public health · 2020Article
- Dual X-Ray absorptiometry leg length in youth.Journal of clinical densitometry : the official journal of the International Society for Clinical DensitometryArticle
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14 authors at 6 institutions in 5 countries.
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Abstract
Early-life experiences may fuel the emergence of obesity and type 2 diabetes among African populations. We evaluated childhood socio-economic status (SES) and childhood nutritional status as risk factors for increased waist circumference and type 2 diabetes among Ghanaian adults. In the multi-center, cross-sectional Research on Obesity and Diabetes among African Migrants (RODAM) Study, we calculated associations (adjusted for demographics and lifestyle) of parental education and anthropometric markers of childhood nutrition [leg length, leg length-to-height ratio (LHR)] with waist circumference and type 2 diabetes, respectively. Among 5,575 participants (mean age: 46.2 years; 62% female), lower education of either parent (vs. higher) was consistently associated with higher waist circumference (∆: 1.6-3.4 cm). Lower father's education tended to increase the odds of type 2 diabetes by 50% in women (95% confidence interval (CI): 1.0, 2.4). Reduced leg length and LHR were associated with higher waist circumference. But only in men, leg length was inversely related to type 2 diabetes (OR per 1 standard deviation decrease: 1.1; 95% CI: 1.0, 1.3). In this study, markers of poor childhood SES and early-life nutritional status relate to abdominal obesity in men and women and to type 2 diabetes in men. Thus, prevention efforts should start in early childhood.
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