ArticleScientific reports2019
Cochlear shape reveals that the human organ of hearing is sex-typed from birth.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 42 citations in OpenAlex.
- Hearing Aid Use Attenuates the Association Between Hearing Loss and Frailty: A 2003-2018 NHANES Cross Sectional Analysis.Journal of the American Geriatrics Society · 2026Article
- Morphometric study of the bony labyrinth of the inner ear in the European moles Talpa europaea, Talpa occidentalis, and Talpa aquitania.Journal of anatomy · 2026Article
- Infant craniofacial diversity in Early Pleistocene Homo.Nature communications · 2025Article
- Sex and environment shape cochlear sensitivity in human populations worldwide.Scientific reports · 2025Article
- Convergent evolution in Afrotheria and non-afrotherians demonstrates high evolvability of the mammalian inner ear.Nature communications · 2024Article
- Training and validation of a deep learning U-net architecture general model for automated segmentation of inner ear from CT.European radiology experimental · 2024Article
- Investigating Additional Cochlear Parameters: A follow-up systematic review and meta-analysis.Journal of otology · 2024Review
- Sex determination by linear measurements of the bony labyrinth in cone-beam and computed tomography: a practical method.Forensic science, medicine, and pathology · 2024Article
- Insular dwarfism in horses from the Aegean Sea and the Japanese archipelago.Mammalian biology = Zeitschrift fur Saugetierkunde · 2024Article
- Hominin fossils from Kromdraai and Drimolen informScience advances · 2023Article
- Size and shape of the semicircular canal of the inner ear: A new marker of pig domestication?Journal of experimental zoology. Part B, Molecular and developmental evolution · 2022Article
- Shape-changing chains for morphometric analysis of 2D and 3D, open or closed outlines.Scientific reports · 2021Article
- Cochlear shape distinguishes southern African early hominin taxa with unique auditory ecologies.Scientific reports · 2021Article
- Local Cisplatin Delivery in Mouse Reliably Models Sensorineural Ototoxicity Without Systemic Adverse Effects.Frontiers in cellular neuroscience · 2021Article
- Human bony labyrinth dataset: Co-registered CT and micro-CT images, surface models and anatomical landmarks.Data in brief · 2019Article
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Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sex differences in behavioral and neural characteristics can be caused by cultural influences but also by sex-based differences in neurophysiological and sensorimotor features. Since signal-response systems influence decision-making, cooperative and collaborative behaviors, the anatomical or physiological bases for any sex-based difference in sensory mechanisms are important to explore. Here, we use uniform scaling and nonparametric representations of the human cochlea, the main organ of hearing that imprints its adult-like morphology within the petrosal bone from birth. We observe a sex-differentiated torsion along the 3D cochlear curve in samples of 94 adults and 22 juvenile skeletons from cross-cultural contexts. The cochlear sexual dimorphism measured in our study allows sex assessment from the human skeleton with a mean accuracy ranging from 0.91 to 0.93 throughout life. We conclude that the human cochlea is sex-typed from an early post-natal age. This, for the first time, allows nondestructive sex determination of juveniles' skeletal remains in which the biomolecules are too degraded for study but in which the petrosal is preserved, one of the most common bone within archaeological assemblages. Our observed sex-typed cochlear shape from birth is likely associated with complex evolutionary processes in modern humans for reasons not yet fully understood.
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