Evidence map›Paper›PMID 31350359›Full record

ArticlePediatrics2019

Pediatric Respiratory Illness Measurement System (PRIMES) Scores and Outcomes.

Rita Mangione-Smith, Chuan Zhou, Derek J Williams, David P Johnson, Chén C Kenyon, Amy Tyler, Ricardo Quinonez, Joyee Vachani, Julie McGalliard, Joel S Tieder and 3 more

Abstract read
In one paragraph

Article in Pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
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  7. Article
  8. Performance of Pediatric Readmission Measures.Journal of hospital medicine · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Rita Mangione-SmithSeattle Children's Research Institute, Seattle Children's Hospital, Seattle, Washington; rita.mangione-smith@seattlechildrens.org.
Chuan ZhouSeattle Children's Research Institute, Seattle Children's Hospital, Seattle, Washington.
Derek J WilliamsDivision of Hospital Medicine, Department of Pediatrics, School of Medicine, Vanderbilt University and Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, Tennessee.
David P JohnsonDivision of Hospital Medicine, Department of Pediatrics, School of Medicine, Vanderbilt University and Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, Tennessee.
Chén C KenyonDepartment of Pediatrics, School of Medicine, University of Pennsylvania and Center for Pediatric Clinical Effectiveness, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Amy TylerDepartment of Pediatrics, School of Medicine, University of Colorado and Section of Hospital Medicine, Children's Hospital Colorado, Aurora, Colorado.
Ricardo QuinonezSection of Pediatric Hospital Medicine, Department of Pediatrics, Baylor College of Medicine, Houston, Texas; and.
Joyee VachaniSection of Pediatric Hospital Medicine, Department of Pediatrics, Baylor College of Medicine, Houston, Texas; and.
Julie McGalliardSeattle Children's Research Institute, Seattle Children's Hospital, Seattle, Washington.
Joel S TiederSeattle Children's Research Institute, Seattle Children's Hospital, Seattle, Washington.
Tamara D SimonSeattle Children's Research Institute, Seattle Children's Hospital, Seattle, Washington.
Karen M WilsonDepartment of Pediatrics, Icahn School of Medicine at Mount Sinai, New York City, New York.
Pediatric Research in Inpatient Settings (PRIS) Network

Funding

The Mount Sinai Transdisciplinary Center on Early Environmental ExposuresP30ES023515 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Maria Jose Rosa · 2014 to 2026
$21.3M
Pediatric Respiratory Illness Measurement System (PRIMES) Implementation in Community Hospital SettingsR01HL121067 · NHLBI · SEATTLE CHILDREN'S HOSPITAL · PI MANGIONE-SMITH, RITA · 2014 to 2025
$6.4M
Incentive-based Mobile Health Adherence Intervention for High Risk Children with AsthmaK23HL136842 · NHLBI · CHILDREN'S HOSP OF PHILADELPHIA · PI KENYON, CHEN COLLIN · 2019 to 2023
$908k
AHRQ HHS K08 HS026512NHLBI NIH HHS K23 HL136842NHLBI NIH HHS R01 HL121067NIEHS NIH HHS P30 ES023515
6 · The paper itself

Abstract

BACKGROUND AND

objectivesThe Pediatric Respiratory Illness Measurement System (PRIMES) generates condition-specific composite quality scores for asthma, bronchiolitis, croup, and pneumonia in hospital-based settings. We sought to determine if higher PRIMES composite scores are associated with improved health-related quality of life, decreased length of stay (LOS), and decreased reuse.

methodsWe conducted a prospective cohort study of 2334 children in 5 children's hospitals between July 2014 and June 2016. Surveys administered on admission and 2 to 6 weeks postdischarge assessed the Pediatric Quality of Life Inventory (PedsQL). Using medical records data, 3 PRIMES scores were calculated (0-100 scale; higher scores = improved adherence) for each condition: an overall composite (including all quality indicators for the condition), an overuse composite (including only indicators for care that should not be provided [eg, chest radiographs for bronchiolitis]), and an underuse composite (including only indicators for care that should be provided [eg, dexamethasone for croup]). Multivariable models assessed relationships between PRIMES composite scores and (1) PedsQL improvement, (2) LOS, and (3) 30-day reuse.

resultsFor every 10-point increase in PRIMES overuse composite scores, LOS decreased by 8.8 hours (95% confidence interval [CI] -11.6 to -6.1) for bronchiolitis, 3.1 hours (95% CI -5.5 to -1.0) for asthma, and 2.0 hours (95% CI -3.9 to -0.1) for croup. Bronchiolitis overall composite scores were also associated with shorter LOS. PRIMES composites were not associated with PedsQL improvement or reuse.

conclusionsBetter performance on some PRIMES condition-specific composite measures is associated with decreased LOS, with scores on overuse quality indicators being a primary driver of this relationship.

Indexed as

ChildChild, PreschoolCohort StudiesFemaleHospitals, PediatricHumansMaleProspective StudiesRespiratory Tract DiseasesTreatment Outcome

Identifiers

PMID31350359
PMCPMC6855826

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.