Evidence map›Paper›PMID 31350355›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2019

Genetic Variation in Surfactant Protein-A2 Delays Resolution of Eosinophilia in Asthma.

Alane Blythe C Dy, Muhammad Z Arif, Kenneth J Addison, Loretta G Que, Scott Boitano, Monica Kraft, Julie G Ledford

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. SURFACTANT PROTEIN A: AN INNATE IMMUNE MODULATOR AND THERAPEUTIC IN ASTHMA.Transactions of the American Clinical and Climatological Association · 2024
    Review
  3. Article
  4. Novel potential treatable traits in asthma: Where is the research taking us?The journal of allergy and clinical immunology. Global · 2022
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Surfactant Protein-A Protects against IL-13-Induced Inflammation in Asthma.Journal of immunology (Baltimore, Md. : 1950) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Alane Blythe C DyClinical Translational Sciences, University of Arizona Health Sciences, Tucson, AZ 85721.
Muhammad Z ArifDepartment of Medicine, University of Arizona, Tucson, AZ 85724.
Kenneth J AddisonAsthma and Airway Disease Research Center, Tucson, AZ 85724.
Loretta G QueDepartment of Medicine, Duke University School of Medicine, Durham, NC 27710; and.ORCID 0000-0001-9188-9244
Scott BoitanoAsthma and Airway Disease Research Center, Tucson, AZ 85724.
Monica KraftAsthma and Airway Disease Research Center, Tucson, AZ 85724.
Julie G LedfordAsthma and Airway Disease Research Center, Tucson, AZ 85724; jledford@email.arizona.edu.
University of Arizona · USDuke University · US

Funding

SOUTHWEST ENVIRONMENTAL HEALTH SCIENCES CENTERP30ES006694 · NIEHS · UNIVERSITY OF ARIZONA · PI DEAN BILLHEIMER · 1994 to 2026
$36.7M
Tollip inhibits IL-33 signaling during airway influenza virus infectionU19AI125357 · NIAID · UNIVERSITY OF ARIZONA · PI CHU, HONG W · 2016 to 2025
$14.7M
Surfactant Protein-A regulation of eosinophil apoptosis in asthmaR01HL125602 · NHLBI · UNIVERSITY OF ARIZONA · PI LEDFORD, JULIE GUNNELLS · 2015 to 2019
$1.9M
Surfactant Protein A as a Novel Therapeutic for AsthmaR21AI135935 · NIAID · UNIVERSITY OF ARIZONA · PI LEDFORD, JULIE GUNNELLS, MANSOUR, HEIDI M. · 2018 to 2019
$422k
NHLBI NIH HHS R01 HL125602NIAID NIH HHS R21 AI135935NIAID NIH HHS U19 AI125357NIEHS NIH HHS P30 ES006694
6 · The paper itself

Abstract

Surfactant protein-A (SP-A) is an important mediator of pulmonary immunity. A specific genetic variation in

Indexed as

AnimalsApoptosisAsthmaChemokine CCL11EosinophiliaGenetic VariationHumansMiceMice, Inbred C57BLPulmonary Surfactant-Associated Protein AChemokine CCL11Pulmonary Surfactant-Associated Protein A

Identifiers

PMID31350355
PMCPMC6702058
OpenAlexW2965135091

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.