Evidence map›Paper›PMID 31350336›Full record

ArticleThe Journal of biological chemistry2019

Ribosome profiling of selenoproteins

Wenchao Zhao, Simon Bohleber, Henrik Schmidt, Sandra Seeher, Michael T Howard, Doreen Braun, Simone Arndt, Uschi Reuter, Hagen Wende, Carmen Birchmeier and 2 more

Abstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Human Genetic Disorders Resulting in Systemic Selenoprotein Deficiency.International journal of molecular sciences · 2021
    Review
  6. Review
  7. The Effect of tRNAInternational journal of molecular sciences · 2021
    Article
  8. SECISBP2 is a novel prognostic predictor that regulates selenoproteins in diffuse large B-cell lymphoma.Laboratory investigation; a journal of technical methods and pathology · 2021
    Article
  9. Article
  10. Review
  11. Article
  12. Bioinformatics of Selenoproteins.Antioxidants & redox signaling · 2020
    Review
  13. Wish you were here: Meetings, no meetings, meeting reports.The Journal of biological chemistry · 2020
    Article
  14. Article
  15. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Wenchao ZhaoInstitut für Biochemie und Molekularbiologie, Rheinische Friedrich-Wilhelms-Universität Bonn, 53115 Bonn, Germany.
Simon BohleberInstitut für Biochemie und Molekularbiologie, Rheinische Friedrich-Wilhelms-Universität Bonn, 53115 Bonn, Germany.
Henrik SchmidtInstitut für Biochemie und Molekularbiologie, Rheinische Friedrich-Wilhelms-Universität Bonn, 53115 Bonn, Germany.
Sandra SeeherInstitut für Biochemie und Molekularbiologie, Rheinische Friedrich-Wilhelms-Universität Bonn, 53115 Bonn, Germany.
Michael T HowardDepartment of Genetics, University of Utah, Salt Lake City, Utah 84112.
Doreen BraunInstitut für Biochemie und Molekularbiologie, Rheinische Friedrich-Wilhelms-Universität Bonn, 53115 Bonn, Germany.
Simone ArndtInstitut für Biochemie und Molekularbiologie, Rheinische Friedrich-Wilhelms-Universität Bonn, 53115 Bonn, Germany.
Uschi ReuterInstitut für Biochemie und Molekularbiologie, Rheinische Friedrich-Wilhelms-Universität Bonn, 53115 Bonn, Germany.
Hagen WendeMax Delbrück Center of Molecular Medicine, 13125 Berlin, Germany.
Carmen BirchmeierMax Delbrück Center of Molecular Medicine, 13125 Berlin, Germany.
Noelia Fradejas-VillarInstitut für Biochemie und Molekularbiologie, Rheinische Friedrich-Wilhelms-Universität Bonn, 53115 Bonn, Germany.
Ulrich SchweizerInstitut für Biochemie und Molekularbiologie, Rheinische Friedrich-Wilhelms-Universität Bonn, 53115 Bonn, Germany Ulrich.schweizer@uni-bonn.de.ORCID 0000-0003-1380-4780

Funding

The effects of dietary selenium on translational control of protein synthesisR01GM114291 · NIGMS · UNIVERSITY OF UTAH · PI HOWARD, MICHAEL T · 2015 to 2022
$2.4M
NIGMS NIH HHS R01 GM114291
6 · The paper itself

Abstract

Recoding of UGA codons as selenocysteine (Sec) codons in selenoproteins depends on a selenocysteine insertion sequence (SECIS) in the 3'-UTR of mRNAs of eukaryotic selenoproteins. SECIS-binding protein 2 (SECISBP2) increases the efficiency of this process. Pathogenic mutations in

Indexed as

Mutation, MissenseAnimalsBinding SitesBrainLiverMetabolism, Inborn ErrorsMiceMice, Inbred C57BLPhenotypeProtein BindingProtein StabilityProteolysisRibosomesRNA-Binding ProteinsSelenocysteineSelenoproteinsRNA-Binding ProteinsSECIS-binding protein 2, mouseSelenocysteineSelenoproteinsbraindeiodinaseliverneurobiologyneuroinflammationSbp2SECIS-binding protein 2 (SECISBP2)seleniumselenocysteineselenocysteine insertion sequence (SECIS)selenoproteinthermal instabilitythyroid hormonetranslation

Identifiers

PMID31350336
PMCPMC6768643

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.