Evidence map›Paper›PMID 31350104›Full record

ArticleHPB : the official journal of the International Hepato Pancreato Biliary Association2020

Association of preoperative biliary drainage technique with postoperative outcomes among patients with resectable hepatobiliary malignancy.

Q Lina Hu, Jason B Liu, Ryan J Ellis, Jessica Y Liu, Anthony D Yang, Michael I D'Angelica, Clifford Y Ko, Ryan P Merkow

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in HPB : the official journal of the International Hepato Pancreato Biliary Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Outcomes with Preoperative Biliary Stenting After Pancreaticoduodenectomy In the Modern Era.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Q Lina HuDivision of Research and Optimal Patient Care, American College of Surgeons, Chicago, IL, USA; Department of Surgery, David Geffen School of Medicine at University of California, Los Angeles, CA, USA.
Jason B LiuDivision of Research and Optimal Patient Care, American College of Surgeons, Chicago, IL, USA; Department of Surgery, University of Chicago, Chicago, IL, USA.
Ryan J EllisDivision of Research and Optimal Patient Care, American College of Surgeons, Chicago, IL, USA; Surgical Outcomes and Quality Improvement Center, Department of Surgery, Feinberg School of Medicine at Northwestern University, Chicago, IL, USA.
Jessica Y LiuDivision of Research and Optimal Patient Care, American College of Surgeons, Chicago, IL, USA; Department of Surgery, Emory University, Atlanta, GA, USA.
Anthony D YangSurgical Outcomes and Quality Improvement Center, Department of Surgery, Feinberg School of Medicine at Northwestern University, Chicago, IL, USA.
Michael I D'AngelicaMemorial Sloan Kettering Cancer Center, New York, NY, USA.
Clifford Y KoDivision of Research and Optimal Patient Care, American College of Surgeons, Chicago, IL, USA; Department of Surgery, David Geffen School of Medicine at University of California, Los Angeles, CA, USA.
Ryan P MerkowDivision of Research and Optimal Patient Care, American College of Surgeons, Chicago, IL, USA; Surgical Outcomes and Quality Improvement Center, Department of Surgery, Feinberg School of Medicine at Northwestern University, Chicago, IL, USA. Electronic address: Ryan.Merkow@northwestern.edu.
American College of Surgeons · USNorthwestern University · USEmory University · USMemorial Sloan Kettering Cancer Center · USUniversity of California, Los Angeles · USUniversity of Chicago · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
PA-20-072: Supplement to A Chicago Center of Excellence in Learning Health Systems Research Training (ACCELERAT)K12HS026385 · AHRQ · NORTHWESTERN UNIVERSITY AT CHICAGO · PI FRANKLIN, PATRICIA D, KHO, ABEL N. · 2018 to 2022
$3.4M
AHRQ HHS HHSP233201500020IAHRQ HHS K12 HS023011AHRQ HHS K12 HS026385AHRQ HHS T32 HS000078NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

backgroundEndoscopic biliary stenting (EBS) and percutaneous transhepatic biliary drainage (PTBD) are two techniques used for preoperative biliary drainage prior to hepatobiliary resection. The objectives of this study were to determine predictors of the drainage technique selection and to evaluate the association between drainage technique and postoperative outcomes.

methodsUsing ACS NSQIP data (2014-2017), patients who underwent preoperative biliary drainage prior to hepatobiliary resection for malignancy were identified. Separate multivariable-adjusted, propensity score (PS) adjusted, and PS matched logistic regression models were constructed to evaluate the association between drainage technique and postoperative outcomes.

resultsOf 527 patients identified, 431 (81.8%) received EBS and 96 (18.2%) received PTBD. Patients who underwent PTBD had more preoperative co-morbidities, including higher ASA class, recent weight loss, and hypoalbuminemia (all p < 0.05). After multivariable adjustment, PTBD was significantly associated with 30-day DSM (OR 1.92, 95% CI 1.24-2.97, p = 0.004), overall SSI (OR 1.74, 95% CI 1.10-2.76, p = 0.019), and superficial SSI (OR 2.08, 95% CI 1.20-3.60, p = 0.010). These findings remained significant for both PS-adjusted and PS-matched models.

conclusionPatients undergoing hepatobiliary resection selected for PTBD had significantly more preoperative co-morbidities and nutritional deficits. Compared to EBS, PTBD was associated with significantly higher odds of postoperative morbidity and mortality.

Indexed as

AgedBiliary Tract NeoplasmsCholestasisDatabases, FactualDisease-Free SurvivalDrainageEndoscopyFemaleHumansLiver NeoplasmsLogistic ModelsMaleMiddle AgedPatient SelectionPostoperative ComplicationsPropensity Score

Identifiers

PMID31350104
PMCPMC8319720
OpenAlexW2964010027

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.