Evidence map›Paper›PMID 31350077›Full record

ArticlePancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]2019

Period prevalence of chronic pancreatitis diagnosis from 2001-2013 in the commercially insured population of the United States.

Jorge D Machicado, Anwar Dudekula, Gong Tang, Hongzhi Xu, Bechien U Wu, Chris E Forsmark, Dhiraj Yadav

Open access · greenAbstract read
In one paragraph

Article in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Idiopathic chronic pancreatitis: clinical highlights.Therapeutic advances in gastroenterology · 2026
    Review
  4. Article
  5. Article
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  8. Review
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  10. Article
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  13. Spectrum ofSovremennye tekhnologii v meditsine · 2023
    Article
  14. Article
  15. The deleterious effects of smoking on the development and progression of chronic pancreatitis.Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] · 2022
    Review
  16. An ethical analysis of endoscopic therapy decision-making in patients with refractory substance use disorder and chronic pancreatitis.Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] · 2022
    Review
  17. Article
  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 1 country.

Jorge D MachicadoDivision of Gastroenterology and Hepatology, Mayo Clinic Health System, Eau Claire, WI, USA.
Anwar DudekulaDivision of Gastroenterology, Saint Peter's University Hospital, New Brunswick, NJ, USA.
Gong TangDepartment of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.
Hongzhi XuDepartment of Health Outcomes and Biomedical Informatics, University of Florida, Gainesville, FL, USA.
Bechien U WuCenter for Pancreatic Care, Division of Gastroenterology, Kaiser Permanente Los Angeles Medical Center, Los Angeles, CA, USA.
Chris E ForsmarkDivision of Gastroenterology, Hepatology, and Nutrition, University of Florida, Gainesville, FL, USA.
Dhiraj YadavDivision of Gastroenterology and Hepatology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA. Electronic address: yadavd@upmc.edu.
Kaiser Permanente · USMayo Clinic Health System · USSaint Peter's University Hospital · USUniversity of Florida · USUniversity of Florida Health · USUniversity of Pittsburgh · USUniversity of Pittsburgh Medical Center · US

Funding

UPMC Clinical Center for the Study of Chronic Pancreatitis and DiabetesU01DK108306 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Frederico G. S. Toledo, Dhiraj Yadav · 2015 to 2026
$6.4M
U-01 CONSORTIUM FOR THE STUDY OF CHRONIC PANCREATITIS,DIABETES AND PANCREATIC CANCER CLINICAL CENTERSU01DK108320 · NIDDK · UNIVERSITY OF FLORIDA · PI CUSI, KENNETH, FORSMARK, CHRISTOPHER E · 2015 to 2024
$4.6M
NIDDK NIH HHS U01 DK108306NIDDK NIH HHS U01 DK108320
6 · The paper itself

Abstract

backgroundPrevalence estimates of chronic pancreatitis (CP) in the US are scarce. We aimed to determine the prevalence of CP in the commercially insured population of the US.

methodsWe analyzed the IQVIA Legacy PharMetrics database to calculate the period prevalence of CP from 2001 to 2013 among individuals with ≥1 year of enrollment. CP was defined as ≥1 healthcare contacts associated with a non-ancillary claim for a primary diagnosis of CP (ICD-9-CM 577.1). Prevalence estimates were age- and sex- adjusted to the 2010 US population. Sensitivity analysis was performed by using more stringent criteria: a) 1 claim of CP + [≥1 claims of acute pancreatitis (AP), CP or pancreatic cyst/pseudocyst]; b) 1 claim of CP + [≥1 claims for AP, CP or pancreatic cyst/pseudocyst in ≥3 months before or after the index CP claim]; c) ≥2 claims for CP; and d) ≥2 claims for CP separated by ≥ 6 months.

resultsOf 48.67 million eligible enrollees, 37,061 received the diagnosis of CP (mean age, 51.2 ± 15.2 years; 49% male). The age- and sex- adjusted period prevalence of CP per 100,000 was 73.4 (95% CI, 72.6-74.1), 98.7 (95% CI, 97.7-99.7) for adults and 8.3 (95% CI, 7.8-8.8) for children. Prevalence of CP was slightly higher in males (sex ratio, 1.05) and highest in the age group of 46-55 years (135/100,000). On sensitivity analysis, the prevalence of CP per 100,000 decreased to 60.2, 39.7, 38.8, and 18.8 with each of the alternative definitions.

conclusionPrevalence estimates reported in our study provide an insight into the population burden of CP in the US.

Indexed as

AdolescentAdultAgedAge FactorsDatabases, FactualFemaleHumansInsurance, HealthMaleMiddle AgedPancreatitis, ChronicPrevalenceRetrospective StudiesSex FactorsUnited StatesYoung AdultBurdenChronic pancreatitisEpidemiologyPopulationPrevalence

Identifiers

PMID31350077
PMCPMC6756969
OpenAlexW2958324536

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.