ReviewAdvances in cancer research2019
Marine natural products in the discovery and development of potential pancreatic cancer therapeutics.
Review in Advances in cancer research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 11 citations in OpenAlex.
- Photocatalytic Generation of Divalent Lanthanide Reducing Agents.Journal of the American Chemical Society · 2023Article
- Ar-turmerone inhibits the proliferation and mobility of glioma by downregulating cathepsin B.Aging · 2023Article
- Terpinen-4-ol Induces Ferroptosis of Glioma Cells via Downregulating JUN Proto-Oncogene.Molecules (Basel, Switzerland) · 2023Article
- Molecular Research in Pancreatic Cancer: Small Molecule Inhibitors, Their Mechanistic Pathways and Beyond.Current issues in molecular biology · 2023Review
- Depsipeptides Targeting Tumor Cells: Milestones from In Vitro to Clinical Trials.Molecules (Basel, Switzerland) · 2023Review
- Mining the candidate genes of rice panicle traits via a genome-wide association study.Frontiers in genetics · 2023Article
- Terpinen-4-ol inhibits the proliferation and mobility of pancreatic cancer cells by downregulating Rho-associated coiled-coil containing protein kinase 2.Bioengineered · 2022Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Pancreatic cancer one of the most deadly cancers and is an increasingly significant concern for global health. The death rates for pancreatic cancer have changed little over time, even with recent expansions of first-line drugs to treat pancreatic cancer there has been little improvement in patient prognosis. Any improvements in treatment strategies will come as a much-needed reprieve to patients diagnosed with this uniquely-challenging disease. Greater attention is needed regarding the identification and development of novel chemotherapeutic strategies with unique mechanisms of action. The marine environment with its particularity has provided a diverse source of novel structural compounds with interesting activities. The marine natural products reported from 2006 to 2018 with compelling activity and potential for the control of pancreatic cancer based on in vitro and in vivo results will be summarized. A key goal of this review is to draw attention to those molecules that warrant additional preclinical development studies.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.