Evidence map›Paper›PMID 31349820›Full record

ArticleBMC nephrology2019

Prevalence, clinical characteristics, and predictors of peripheral arterial disease in hemodialysis patients: a cross-sectional study.

Radislav R Ašćerić, Nada B Dimković, Goran Ž Trajković, Biljana S Ristić, Aleksandar N Janković, Petar S Durić, Nenad S Ilijevski

Open access · goldAbstract read
In one paragraph

Article in BMC nephrology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Radislav R AšćerićDepartment of Vascular Surgery Clinic of Surgery, Clinical Hospital Center Zvezdara, Dimitrija Tucovića 161, Belgrade, 11000, Serbia. radislavasceric@gmail.com.ORCID 0000-0002-9729-5612
Nada B DimkovićClinic of Nephrology, Clinical Hospital Center Zvezdara, Belgrade, Serbia.
Goran Ž TrajkovićDepartment of Medical Statistics and Informatics Medical Faculty, University of Belgrade, Belgrade, Serbia.
Biljana S RistićPrimary Health Center, Palilula, Belgrade, Serbia.
Aleksandar N JankovićClinic of Nephrology, Clinical Hospital Center Zvezdara, Belgrade, Serbia.
Petar S DurićClinic of Nephrology, Clinical Hospital Center Zvezdara, Belgrade, Serbia.
Nenad S IlijevskiMedical Faculty, University of Belgrade, Belgrade, Serbia.
Kliničko Bolnički Centar Zvezdara · RSUniversity of Belgrade · RS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeripheral arterial disease (PAD) is common in patients with end-stage renal disease on hemodialysis, but is frequently underdiagnosed. The risk factors for PAD are well known within the general population, but they differ somewhat in hemodialysis patients. This study aimed to determine the prevalence of PAD and its risk factors in patients on hemodialysis.

methodsThis cross-sectional study included 156 hemodialysis patients. Comorbidities and laboratory parameters were analyzed. Following clinical examinations, the ankle-brachial index was measured in all patients. PAD was diagnosed based on the clinical findings, ankle-brachial index < 0.9, and PAD symptoms.

resultsPAD was present in 55 of 156 (35.3%; 95% CI, 27.7-42.8%) patients. The patients with PAD were significantly older (67 ± 10 years vs. 62 ± 11 years, p = 0.014), more likely to have diabetes mellitus (p = 0.022), and anemia (p = 0.042), and had significantly lower serum albumin (p = 0.005), total cholesterol (p = 0.024), and iron (p = 0.004) levels, higher glucose (p = 0.002) and C-reactive protein (p < 0.001) levels, and lower dialysis adequacies (p = 0.040) than the patients without PAD. Multivariate analysis showed higher C-reactive protein level (odds ratio [OR], 1.03; 95% confidence interval [CI], 1.00-1.06; p = 0.030), vascular access by Hickman catheter (OR, 4.66; 95% CI, 1.03-21.0; p = 0.045), and symptoms of PAD (OR, 5.20; 95% CI, 2.60-10.4; p < 0.001) as independent factors associated with PAD in hemodialysis patients.

conclusionThe prevalence of PAD was high among patients with end-stage renal disease on hemodialysis. Symptoms of PAD, higher C-reactive protein levels, and Hickman vascular access were independent predictors of PAD in patients on hemodialysis.

Indexed as

Renal DialysisAgedCross-Sectional StudiesFemaleHumansKidney Failure, ChronicMaleMiddle AgedPeripheral Arterial DiseasePrevalenceRisk FactorsAnkle-brachial indexC-reactive proteinHemodialysisHickman vascular accessPeripheral arterial disease

Identifiers

PMID31349820
PMCPMC6660935
OpenAlexW2965274835

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.