ArticleBMC infectious diseases2019
Risk factors for acquisition of scrub typhus in children admitted to a tertiary centre and its surrounding districts in South India: a case control study.
Article in BMC infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Unveiling the burden of scrub typhus in acute febrile illness cases across India: A systematic review & meta-analysis.The Indian journal of medical research · 2024Pooled it
- Epidemiology and risk factors in a scrub typhus cluster in Odisha, India, 2023: Investigating with a One Health approach.One health outlook · 2026Article
- Leptotrombidium imphalum Chiggers as Vector for Scrub Typhus in Human Settlements, India, 2022-2023.Emerging infectious diseases · 2026Article
- Associations between meteorological factors and scrub typhus incidence: a systematic review and meta-analysis of linear and nonlinear dose-response relationships.Tropical medicine and health · 2025Article
- Risk factors for scrub typhus infection in South India: population-based cohort study.Epidemiology and infection · 2025Observational
- The Association Between Environmental Factors and Scrub Typhus: A Review.Tropical medicine and infectious disease · 2025Review
- Community engagement around scrub typhus in northern Thailand: a pilot project.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2024Article
- Prevalence of and factors associated with scrub typhus exposure among the hill tribe population living in high incidence areas in Thailand: a cross-sectional study.BMC public health · 2023Article
- Urine Metabolite of Mice with Orientia tsutsugamushi Infection.The American journal of tropical medicine and hygiene · 2023Article
- Ecological and behavioural risk factors of scrub typhus in central Vietnam: a case-control study.Infectious diseases of poverty · 2021Article
- Seasonal abundance of Leptotrombidium deliense, the vector of scrub typhus, in areas reporting acute encephalitis syndrome in Gorakhpur district, Uttar Pradesh, India.Experimental & applied acarology · 2021Article
- Diagnosis of scrub typhus: recent advancements and challenges.3 Biotech · 2020Review
- Risk Factors for Scrub Typhus, Murine Typhus, and Spotted Fever Seropositivity in Urban Areas, Rural Plains, and Peri-Forest Hill Villages in South India: A Cross-Sectional Study.The American journal of tropical medicine and hygiene · 2020Article
- Risk Factors Associated with Adult Scrub Typhus Cases in a Tertiary Care Hospital - A Case Control Study.Indian journal of community medicine : official publication of Indian Association of Preventive & Social MedicineArticle
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundScrub typhus is a mite borne zoonosis common in the tropics with no good preventive strategy. Children are also affected leading to considerable morbidity and mortality. We conducted a case control study and a vector survey to determine the risk factors for acquisition of scrub typhus.
methodsA case control study with a 1:2 case control ratio was conducted over a 2 year period at a tertiary care centre and its surrounding districts in South India. Cases were children < 15 years with confirmed scrub typhus. Controls were age and locality matched community controls without fever. Demographic, environmental and behavioural risk factors were obtained in cases and controls by an interview and an environmental survey. A vector survey was also undertaken in the immediate vicinity of the cases.
resultsCase Control study: 101 cases and 167 controls were analysed. On multivariate analysis, significant association was observed with environmental factors such as the presence of a water body within 100 m of the house (OR 3.56(1.36,9.75); p 0.011), cooking outside the house (OR 5.61 (1.51,23.01); p 0.011), owning pets (OR 3.33(1.16,9.09); p 0.031), and the presence of bushes within 5 m of the house (OR 2.78 (1.11,7.69); p 0.033). Of the behavioural factors, the child going to school by a vehicle (OR 3.12 (2.29,8.37); p 0.006) was associated with an increased risk. Drying clothes on a clothesline showed a trend towards protection from acquiring scrub typhus (OR 0.31 (0.08, 1.08); p 0.077). Vector survey:26 rodents were trapped in as many houses. Trombiculid mites were isolated in 24 houses with 9(34.6%) being able to transmit scrub typhus. 254 trombiculid mites belonging to four species and two genera were collected. Leptotrombidium deliense, (33.5%). Schoengastiella ligula, (11.0%) of the total mite specimens collected. S. ligula always co-existed with L. deliense. The estimated Chigger index for Leptotrombidium deliense and Schoengastiella ligula was 3.27and 1.08 per animal respectively.
conclusionsOur study highlights risk factors for scrub typhus, some of which may be modifiable. A clean peri-domestic environment free of vegetation, drying clothes on a clothesline and cooking indoors may decrease the risk of scrub typhus.
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