SynthesisBMC genetics2019
Meta-analysis of the effects of overexpression of WRKY transcription factors on plant responses to drought stress.
Synthesis in BMC genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- The transcription factor ClWRKY61 interacts with ClLEA55 to enhance salt tolerance in watermelon.Horticulture research · 2025Article
- Proline Metabolism Genes in Transgenic Plants: Meta-Analysis under Drought and Salt Stress.Plants (Basel, Switzerland) · 2024Article
- Transcriptome Sequencing and Metabolome Analysis Reveals the Molecular Mechanism of Drought Stress in Millet.International journal of molecular sciences · 2022Article
- Meta-Analysis of the Effect of Overexpression of MYB Transcription Factors on the Regulatory Mechanisms of Anthocyanin Biosynthesis.Frontiers in plant science · 2021Article
- Transcriptome and Co-expression Network Analyses Reveal Differential Gene Expression and Pathways in Response to Severe Drought Stress in Peanut (Frontiers in genetics · 2021Article
- Genetic Analysis of Root-to-Shoot Signaling and Rootstock-Mediated Tolerance to Water Deficit in Tomato.Genes · 2020Article
- RNA-sequencing analysis revealed genes associated drought stress responses of different durations in hexaploid sweet potato.Scientific reports · 2020Article
- The Effect of Drought on Transcriptome and Hormonal Profiles in Barley Genotypes With Contrasting Drought Tolerance.Frontiers in plant science · 2020Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe tryptophan-arginine-lysine-tyrosine (WRKY) transcription factors play important roles in plants, allowing them to adapt to environmental conditions that are not normally conducive to plant growth; in particular, drought. There has been extensive research on WRKY transcription factors and the effects of their overexpression in plants on resistance to drought stress. However, due to the materials (the type and species of donor and receptor, promoters) and treatments (the type and time of stress) used, different and often confounding results have been obtained between studies. Meta-analysis is a powerful statistical tool that can be used to summarize results from numerous independent experiments on the same research topic while accounting for variability across experiments.
resultsWe carried out a meta-analysis of 16 measured parameters that affect drought resistance in plants overexpressing WRKY transcription factors and wild-type plants. We found that only one of these parameters was significantly different between transgenic and wild-type plants under drought and control conditions at a 95% confidence interval (p = 0.000, p = 0.009, respectively). Eleven of the sixteen parameters were obviously different in WRKY transgenic plants under drought and control conditions (SV, p = 0.023, SSC, p = 0.000, SOD, p = 0.012, SFW, p = 0.000, RL, p = 0.016, Pro, p = 0.000, POD, p = 0.027, MDA, p = 0.000, H
conclusionWe have found that only one of these parameters was significantly different between transgenic and wild-type plants under drought and control conditions respectively, at a 95% confidence interval. And eleven of sixteen parameters showed obviously different of WRKY-overexpressed plants under different conditions (water-stressed and normal), suggesting that WRKY transcription factors play an important role in plant responses to drought stress. These findings also provide a theoretical basis for further study of the role of WRKY transcription factors in the regulation of plant responses to environmental stress.
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