Evidence map›Paper›PMID 31349698›Full record

ArticleCells2019

An Exosomal Urinary miRNA Signature for Early Diagnosis of Renal Fibrosis in Lupus Nephritis.

Cristina Solé, Teresa Moliné, Marta Vidal, Josep Ordi-Ros, Josefina Cortés-Hernández

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
90citing papers in PubMed, 6 pooled it
13.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

90 citing papers in PubMed, 6 syntheses or guidelines pooled it, 141 citations in OpenAlex.

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30 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Cristina SoléHospital Universitari Vall d'Hebron, Vall d'Hebron Research Institute (VHIR), Lupus Unit, 08035 Barcelona, Spain. cristina.sole@vhir.org.
Teresa MolinéHospital Universitari Vall d'Hebron, Department of Renal Pathology, 08035 Barcelona, Spain.
Marta VidalHospital Universitari Vall d'Hebron, Department of Renal Pathology, 08035 Barcelona, Spain.
Josep Ordi-RosHospital Universitari Vall d'Hebron, Vall d'Hebron Research Institute (VHIR), Lupus Unit, 08035 Barcelona, Spain.
Josefina Cortés-HernándezHospital Universitari Vall d'Hebron, Vall d'Hebron Research Institute (VHIR), Lupus Unit, 08035 Barcelona, Spain.
Vall d'Hebron Institut de Recerca · ESVall d'Hebron Hospital Universitari · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For lupus nephritis (LN) management, it is very important to detect fibrosis at an early stage. Urinary exosomal miRNAs profiling can be used as a potential multi-marker phenotyping tool to identify early fibrosis. We isolated and characterised urinary exosomes and cellular pellets from patients with biopsy-proven LN (

Indexed as

BiomarkersAdultBiopsyEarly DiagnosisExosomesFemaleFibrosisGene Expression ProfilingHumansImmunohistochemistryLiquid BiopsyLupus NephritisMaleMicroRNAsReal-Time Polymerase Chain ReactionYoung AdultBiomarkersMicroRNAslupus nephritismulti-marker panelrenal fibrosisurinary exosomes

Identifiers

PMID31349698
PMCPMC6721515
OpenAlexW2962781231

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.