Evidence map›Paper›PMID 31349647›Full record

ArticleMolecules (Basel, Switzerland)2019

Screening and Isolating Major Aldose Reductase Inhibitors from the Seeds of Evening Primrose (

Zhiqiang Wang, Shigang Shen, Ze Cui, Hailiang Nie, Dandan Han, Hongyuan Yan

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Foods (Basel, Switzerland) · 2021
    Article
  5. Defatted Seeds ofFoods (Basel, Switzerland) · 2021
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Zhiqiang WangKey Laboratory of Medicinal Chemistry and Molecular Diagnosis, Ministry of Education & College of Public Health, Hebei University, Baoding 071002, China.ORCID 0000-0003-3637-8286
Shigang ShenKey Laboratory of Analytical Science and Technology of Hebei Province, College of Chemistry and Environmental Science, Hebei University, Baoding 071002, China.
Ze CuiHebei Provincial Center for Disease Control and Prevention, Shijiazhuang 050021, China.
Hailiang NieKey Laboratory of Medicinal Chemistry and Molecular Diagnosis, Ministry of Education & College of Public Health, Hebei University, Baoding 071002, China.
Dandan HanKey Laboratory of Medicinal Chemistry and Molecular Diagnosis, Ministry of Education & College of Public Health, Hebei University, Baoding 071002, China.
Hongyuan YanKey Laboratory of Medicinal Chemistry and Molecular Diagnosis, Ministry of Education & College of Public Health, Hebei University, Baoding 071002, China. yanhy@hbu.edu.cn.
Hebei University · CNHebei Provincial Center for Disease Control and Prevention · CN

Funding

Department of Education of Hebei Province BJ2018035Hebei University 801260201199National Natural Science Foundation of China 81803401
6 · The paper itself

Abstract

Aldose reductase (AR) is a drug target for therapies to treat complications caused by diabetes mellitus, and the development of effective AR inhibitors (ARIs) of natural origin is considered to be an attractive option for reducing these complications. In this research, the rat lens AR (RLAR) inhibitory activity of evening primrose (

Indexed as

Aldehyde ReductaseAnimalsChemical FractionationChromatography, High Pressure LiquidDrug Evaluation, PreclinicalEnzyme ActivationEnzyme InhibitorsLens, CrystallineMagnetic Resonance SpectroscopyMolecular StructureOenothera biennisPlant ExtractsRatsSeedsAldehyde ReductaseEnzyme InhibitorsPlant Extractsaldose reductaseevening primrose seedsHSCCCOenothera biennisultrafiltration

Identifiers

PMID31349647
PMCPMC6695788
OpenAlexW2963863844

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.