Evidence map›Paper›PMID 31349088›Full record

ArticleNanomedicine : nanotechnology, biology, and medicine2019

Engineered nanomedicine for neuroregeneration: light emitting diode-mediated superparamagnetic iron oxide-gold core-shell nanoparticles functionalized by nerve growth factor.

Muzhaozi Yuan, Ya Wang, Yi-Xian Qin

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nanomedicine : nanotechnology, biology, and medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 32 citations in OpenAlex.

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  10. Multifunctional hybrid nanoplatform based on FeJournal of materials science. Materials in medicine · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Muzhaozi YuanJ. Mike Walker '66 Department of Mechanical Engineering, Texas A&M University, College Station, TX. Electronic address: muzhaozi.yuan@tamu.edu.
Ya WangJ. Mike Walker '66 Department of Mechanical Engineering, Texas A&M University, College Station, TX. Electronic address: ya.wang@tamu.edu.
Yi-Xian QinDepartment of Biomedical Engineering, Stony Brook University, Stony Brook, NY. Electronic address: yi-xian.qin@stonybrook.edu.
Stony Brook University · USTexas A&M University · USWalker (United States) · US

Funding

ELECTRIC FIELD ATTENUATION OF OSTEOCLAST FORMATIONR01AR042360 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI RUBIN, JANET E · 1993 to 2013
$2.8M
AUGMENTATION OF TRABECULAR BONE BY LOW MAGNITUDE STRAINR01AR043498 · NIAMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI RUBIN, CLINTON T · 1997 to 2012
$2.8M
Functional Fluid Flow Regulated Bone RegenerationR01AR061821 · NIAMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI QIN, YI-XIAN · 2012 to 2016
$1.7M
Role of Musculo-Dynamics in Bone Fluid Flow, Circulation and AdaptationR01AR052379 · NIAMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI QIN, YI-XIAN · 2005 to 2009
$1.7M
Bone Fluid Flow and its Regulatory Role in AdaptationR01AR049286 · NIAMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI QIN, YI-XIAN · 2003 to 2006
$1.1M
NIAMS NIH HHS R01 AR042360NIAMS NIH HHS R01 AR043498NIAMS NIH HHS R01 AR049286NIAMS NIH HHS R01 AR052379NIAMS NIH HHS R01 AR061821
6 · The paper itself

Abstract

This paper reports nerve growth factor functionalized superparamagnetic iron oxide-gold core-shell nanoparticles (NGF-SPIO-Au NPs), an engineered nanomedicine for non-invasive neuron regeneration when irradiated by a low-intensity light-emitting diode (LED). NGF-SPIO-Au NPs of 20 μg/ml, were tested on PC-12 neuron-like cells, irradiated by LEDs (525 nm, 1.09, 1.44, and 1.90 mW/cm

Indexed as

AnimalsCell Adhesion MoleculesCell DifferentiationCell ProliferationCell SurvivalFerric CompoundsGoldHumansLightMagnetite NanoparticlesMetal NanoparticlesNanomedicineNerve Growth FactorNerve RegenerationPC12 CellsRatsCell Adhesion MoleculesFerric Compoundsferric oxideGoldMagnetite NanoparticlesNerve Growth FactorCalcium influxLight emitting diodeNerve regenerationNGF-SPIO-au nanoparticlesPhotothermal effect

Identifiers

PMID31349088
PMCPMC6814551
OpenAlexW2963071589

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.