Evidence map›Paper›PMID 31348840›Full record

ArticleJournal of cardiac surgery2019

Application techniques of a novel hemostat in cardiac operations: HEMOBLAST.

Brian A Bruckner, Uy Ngo, Mahesh Ramchandani, Erik Suarez, Samir Awad, Michael Reardon

Open access · hybridAbstract readCase Reports
In one paragraph

Article in Journal of cardiac surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Brian A BrucknerHouston Methodist Hospital, Methodist DeBakey Heart & Vascular Center, Houston, Texas.ORCID http://orcid.org/0000-0002-0263-5128
Uy NgoHouston Methodist Hospital, Methodist DeBakey Heart & Vascular Center, Houston, Texas.
Mahesh RamchandaniHouston Methodist Hospital, Methodist DeBakey Heart & Vascular Center, Houston, Texas.
Erik SuarezHouston Methodist Hospital, Methodist DeBakey Heart & Vascular Center, Houston, Texas.
Samir AwadDepartment of Surgery, Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas.
Michael ReardonHouston Methodist Hospital, Methodist DeBakey Heart & Vascular Center, Houston, Texas.
Houston Methodist · USMichael E. DeBakey VA Medical Center · US

Funding

Biom'up, Lyon, France
6 · The paper itself

Abstract

backgroundPostoperative bleeding complications are associated with less favorable outcomes in cardiac surgery and contribute to excessive overall healthcare costs. HEMOBLAST (Biom'up, Lyon, France) (HB) is a novel ready-to-use hemostatic powder that consists of porcine collagen, bovine chondroitin sulfate, and human pooled plasma thrombin that may help reduce surgical bleeding.

aimsThe aim of this study was to describe the techniques of application for this new combination powder-based hemostat, HB, and demonstrate its use employing photographs of application methods during cardiac procedures. MATERIALS AND

methodsThe initial 24 procedures in which HB was used at our institution included: left ventricular assist device (LVAD) insertions, lung transplants, heart transplants, aortic valve replacements, coronary artery bypass grafting, and mitral valve repair.

resultsHemostasis was achieved in all cases and there were no instances of mediastinitis, sternal infections, allergic reactions, or 30-day mortality. DISCUSSION: This report describes the best methods of application of HB including use for treatment of mediastinal bleeding in a re-operative procedure in a patient on antiplatelet agents and sternal bleeding during an LVAD insertion. Proper application can facilitate excellent hemostasis using this powder.

conclusionHB is a novel powder-based multiple component hemostatic agent that promotes focal or large area hemostasis. We have presented the techniques of use that are important to the successful application of HB to facilitate hemostasis.

Indexed as

AgedCoronary Artery BypassCoronary Artery DiseaseEquipment DesignFemaleHemostasis, SurgicalHemostaticsHumansMaleMiddle AgedPostoperative HemorrhageHemostaticscardiaccollagenhemostathemostatic powderthrombin

Identifiers

PMID31348840
PMCPMC6773212
OpenAlexW2964964523

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.