Evidence map›Paper›PMID 31348813›Full record

ArticlePloS one2019

Incidence, prevalence and risk factors for hepatitis C in Danish prisons.

Jacob Søholm, Dorte Kinggaard Holm, Belinda Mössner, Lone Wulff Madsen, Janne Fuglsang Hansen, Nina Weis, Agnes Pernille Sauer, Tahany Awad, Peer Brehm Christensen

Abstract readMulticenter Study
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Modeling the Health Economic Burden of Hepatitis C Virus Infection in Turkey: Cost-Effectiveness of Targeted Screening.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2023
    Review
  8. Hepatitis C time trends in reported cases and estimates of the hidden population born before 1965, Denmark and Sweden, 1990 to 2020.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jacob SøholmDepartment of Infectious Diseases, Odense University Hospital, Odense, Denmark.ORCID 0000-0002-7019-2269
Dorte Kinggaard HolmDepartment of Clinical Immunology, Odense University Hospital, Odense, Denmark.
Belinda MössnerDepartment of Infectious Diseases, Odense University Hospital, Odense, Denmark.
Lone Wulff MadsenDepartment of Infectious Diseases, Odense University Hospital, Odense, Denmark.
Janne Fuglsang HansenDepartment of Infectious Diseases, Odense University Hospital, Odense, Denmark.
Nina WeisDepartment of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark.
Agnes Pernille SauerDepartment of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark.
Tahany AwadMedical Affairs, AbbVie A/S, Copenhagen, Denmark.
Peer Brehm ChristensenDepartment of Infectious Diseases, Odense University Hospital, Odense, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis C virus (HCV) infection is prevalent among people in prison and prisons could therefore represent a unique opportunity to test risk groups for HCV. The aim of this sero-epidemiological study was to determine the incidence and prevalence of HCV infection and the corresponding risk factors in Danish prisons. Participants, recruited from eight Danish prisons, were tested for HCV using dried blood spots and filled out a questionaire with demographic data and risk factors for HCV infection. In total, 76.9% (801/1041) of all eligible prisoners consented to participate. The prevalence of HCV RNA positive prisoners was 4.2% (34/801) and the in-prison incidence rate was 0.7-1.0 per 100PY overall and 18-24/100PY among PWIDs. Infected prisoners were older than the overall population with a mean age of 42 years and only 17.6% (6/34) were younger than 35 years. The prevalence of PWID was 8.5% (68/801) and only 3% (2/68) of PWID were younger than 25 years. Among the PWID, 85.3% (58/68) had ever received opioid substitution therapy (OST) and 47.1% (32/68) were currently receiving OST. Risk factors associated with HCV infection were intravenous drug use, age ≥ 40 years, and being incarcerated ≥ 10 years. In conclusion, the prevalence of PWID in Danish prisons is low, possibly reflecting a decrease in injecting among the younger generation. This together with OST coverage could explain the low prevalence of HCV infection. However among PWIDs in prison the incidence remains high, suggesting a need for improved HCV prevention in prison.

Indexed as

AdultDenmarkDried Blood Spot TestingFemaleHepacivirusHepatitis CHumansIncidenceMaleMiddle AgedPrevalencePrisonersRisk AssessmentRNA, ViralSeroepidemiologic StudiesSubstance Abuse, IntravenousRNA, Viral

Identifiers

PMID31348813
PMCPMC6660074

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.