ArticlePloS one2019
Association of metabolic syndrome with the incidence of hearing loss: A national population-based study.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.
- Sensorineural hearing loss and risk of stroke: a systematic review and meta-analysis.Scientific reports · 2021Pooled it
- Genotype-guided Recall Delineates the Adult Auditory Phenotype in GJB2 p.V37I Homozygotes: High-frequency Vulnerability and Environmental Modulation.Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2026Article
- Association of Metabolic Dysfunction-Associated Steatotic Liver Disease With Sudden Sensorineural Hearing Loss Among Older Adults.Laryngoscope investigative otolaryngology · 2025Article
- Polygenic Risk Score-Based Association Analysis Identifies Genetic Comorbidities Associated with Age-Related Hearing Difficulty in Two Independent Samples.Journal of the Association for Research in Otolaryngology : JARO · 2024Article
- Cardiometabolic diseases according to the type and degree of hearing loss in noise-exposed workers.Annals of occupational and environmental medicine · 2024Article
- Association of Metabolic Syndrome with Sensorineural Hearing Loss.Journal of clinical medicine · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND &
aimsSensorineural hearing loss (HL) is one of the most common public health problems, and its prevalence increases with increasing life expectancy. An association between HL and metabolic syndrome (MetS) is suspected. Although previous epidemiological studies have investigated the association between the two variables, there have been conflicting conclusions. Therefore, we aimed to evaluate the association between the presence of MetS-and individual components of MetS-and HL, using a longitudinal design and a large-scale population.
methodsA total of 17,513,555 individuals who underwent national health screening between January 2009 and December 2010 were identified. Subject data from the Korean Health Insurance Review and Assessment Service were reviewed. A total of 11,457,931 subjects were ultimately included in the analysis. Baseline comorbidities were defined according to the ICD-10 code from the Korean Health Insurance Review and Assessment Service data. If the participants had an ICD-10 code for HL during the follow-up, they were defined as having incident HL. Criteria for MetS adhered to the revised National Cholesterol Education Program Adult Treatment Panel III.
resultsThere were 7,574,432 subjects without MetS and 3,883,499 with MetS. The incidence of HL in subjects without MetS and with MetS was 1.3% and 1.8% at 1 year, 4.1% and 5.2% at 3 years, and 6.8% and 8.6% at 5 years, respectively (P < 0.001). However, multivariate analyses revealed a negative association. Analyses according to the components of MetS demonstrated a positive association for those associated with dyslipidemia; however, the others exhibited an inverse association with HL. We also performed analyses using 4 groups according to the presence of MetS and the components of dyslipidemia. Univariate analysis revealed a positive association between the presence of MetS and HL; however, multivariate analysis revealed a positive association between the presence of dyslipidemia components and HL, regardless of the presence of MetS.
conclusionAmong the components of MetS, the association between low HDL or high TG levels and HL was most apparent. It is useful to evaluate each MetS component in isolation, such as the presence of low HDL or high TG levels, rather than the presence of MetS as a cluster of components.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.