Evidence map›Paper›PMID 31348656›Full record

ArticleACS synthetic biology2019

Communicating Structure and Function in Synthetic Biology Diagrams.

Jacob Beal, Tramy Nguyen, Thomas E Gorochowski, Angel Goñi-Moreno, James Scott-Brown, James Alastair McLaughlin, Curtis Madsen, Benjamin Aleritsch, Bryan Bartley, Shyam Bhakta and 14 more

Abstract read
In one paragraph

Article in ACS synthetic biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Data hazards in synthetic biology.Synthetic biology (Oxford, England) · 2024
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Jacob BealBioCoder Consulting , Carlsbad 92008 , California , United States.ORCID 0000-0002-1663-5102
Tramy NguyenUniversity of Utah , Salt Lake City , Utah 84112 , United States.ORCID 0000-0002-8035-0259
Thomas E GorochowskiUniversity of Bristol , Bristol BS8 1TH , U.K.
Angel Goñi-MorenoNewcastle University , Newcastle upon Tyne NE1 7RU , U.K.
James Scott-BrownUniversity of Oxford , Oxford OX1 2JD , U.K.
James Alastair McLaughlinNewcastle University , Newcastle upon Tyne NE1 7RU , U.K.
Curtis MadsenBoston University , Boston , Massachusetts 02215 , United States.
Benjamin AleritschTechnical University of Munich , 80333 München , Germany.
Bryan BartleyRaytheon BBN Technologies , Arlington , Virginia 22209 , United States.ORCID 0000-0002-1597-4022
Shyam BhaktaRice University , Houston , Texas 77005 , United States.
Mike BissellAmyris, Inc. , Emeryville , California 94608 , United States.
Sebastian Castillo HairRice University , Houston , Texas 77005 , United States.
Kevin ClancyBioCoder Consulting , Carlsbad 92008 , California , United States.
Augustin LunaHarvard Medical School , Boston , Massachusetts 02115 , United States.
Nicolas Le NovèreaSciStance Ltd. , Cambridge CB22 3LF , U.K.
Zach PalchickZymergen , Emeryville , California 94608 , United States.
Matthew PocockTuring Ate My Hamster, Ltd. , Tyne And Wear NE27 0RT , U.K.
Herbert SauroUniversity of Washington , Seattle , Washington 98195 , United States.
John T SextonRice University , Houston , Texas 77005 , United States.
Jeffrey J TaborRice University , Houston , Texas 77005 , United States.
Christopher A VoigtMIT , Cambridge , Massachusetts 02139 , United States.ORCID 0000-0003-0844-4776
Zach ZundelUniversity of Utah , Salt Lake City , Utah 84112 , United States.ORCID 0000-0003-1355-6721
Chris MyersUniversity of Utah , Salt Lake City , Utah 84112 , United States.ORCID 0000-0002-8762-8444
Anil WipatNewcastle University , Newcastle upon Tyne NE1 7RU , U.K.ORCID 0000-0001-7310-4191

Funding

TR&D 3 - Network Guided Machine LearningP41GM103504 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI IDEKER, TREY · 2012 to 2024
$17.3M
Pathway Commons: Research Resource for Biological PathwaysU41HG006623 · NHGRI · SLOAN-KETTERING INST CAN RESEARCH · PI SANDER, CHRIS · 2012 to 2017
$5.7M
High Performance Simulation Libraries for Systems BiologyR01GM123032 · NIGMS · UNIVERSITY OF WASHINGTON · PI SAURO, HERBERT M. · 2017 to 2020
$1.7M
Biotechnology and Biological Sciences Research Council BB/L01386X/1NHGRI NIH HHS U41 HG006623NIGMS NIH HHS P41 GM103504NIGMS NIH HHS R01 GM123032
6 · The paper itself

Abstract

Biological engineers often find it useful to communicate using diagrams. These diagrams can include information both about the structure of the nucleic acid sequences they are engineering and about the functional relationships between features of these sequences and/or other molecular species. A number of conventions and practices have begun to emerge within synthetic biology for creating such diagrams, and the Synthetic Biology Open Language Visual (SBOL Visual) has been developed as a standard to organize, systematize, and extend such conventions in order to produce a coherent visual language. Here, we describe SBOL Visual version 2, which expands previous diagram standards to include new functional interactions, categories of molecular species, support for families of glyph variants, and the ability to indicate modular structure and mappings between elements of a system. SBOL Visual 2 also clarifies a number of requirements and best practices, significantly expands the collection of glyphs available to describe genetic features, and can be readily applied using a wide variety of software tools, both general and bespoke.

Indexed as

Programming LanguagesModels, TheoreticalSoftwareSynthetic Biologydiagramssynthetic biologySynthetic Biology Open Languagevisualization

Identifiers

PMID31348656
PMCPMC8023477

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.