ArticleJournal of the American Chemical Society2019
Assembling a Natural Small Molecule into a Supramolecular Network with High Structural Order and Dynamic Functions.
Article in Journal of the American Chemical Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
41 citing papers in PubMed, 360 citations in OpenAlex.
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- Direct Evidence for the Sulfonium-Mediated Photopolymerization of 1,2-Dithiolanes.Journal of the American Chemical Society · 2026Article
- Dynamic Self-Healing Polymer Architectures for High-Performance Flexible Sensing.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- Ammonium Glycyrrhizinate-Reinforced Dual-Network Poly(Thioctic Acid)-Based Hydrogel Dressing with Robust Wet Adhesion, Antibacterial Activity and Oxidative Stress Regulation.Materials (Basel, Switzerland) · 2026Article
- Self-Assembled Nanomaterials for ER-Targeted Cancer Therapy: From Molecular Design to Therapeutic Applications.Biomacromolecules · 2026Review
- Reversible crosslinking strategy for dynamic strain regulation in inverted perovskite solar cells.Nature communications · 2026Article
- Synthesis of poly(ester disulfide)s from SNature communications · 2026Article
- Sulfur-containing sustainable polymers: synthetic pathways, degradation mechanisms, and multifunctional applications.National science review · 2025Review
- Robust and Reversible Supramolecular Adhesive via Dynamic Covalent Bond Crosslinking-Induced Assembly of Metal-Coordinated Nanoparticles.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Dynamic Covalent Sulfur-Selenium Rich Polymers via Inverse Vulcanization for High Refractive Index, High Transmittance, and UV Shielding Materials.Macromolecular rapid communications · 2025Article
- Chemical passivation and grain-boundary manipulation via in situ cross-linking strategy for scalable flexible perovskite solar cells.Science advances · 2025Article
- ExploringPolymers · 2024Article
- Arginine-solubilized lipoic acid-induced β-sheets of silk fibroin-strengthened hydrogel for postoperative rehabilitation of breast cancer.Bioactive materials · 2024Article
- Semi-crystalline polymers with supramolecular synergistic interactions: from mechanical toughening to dynamic smart materials.Chemical science · 2024Review
- Wet environment-induced adhesion and softening of coenzyme-based polymer elastic patch for treating periodontitis.Bioactive materials · 2024Article
- Fast-relaxing hydrogels with reversibly tunable mechanics for dynamic cancer cell culture.Biomaterials advances · 2024Article
- Dynamic Chemistry Toolbox for Advanced Sustainable Materials.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Review
- A Self-Assemble Supramolecular Film with Humidity Visualization Enabled by Clusteroluminescence.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Programming the hierarchical self-assembly of small molecules has been a fundamental topic of great significance in biological systems and artificial supramolecular systems. Precise and highly programmed self-assembly can produce supramolecular architectures with distinct structural features. However, it still remains a challenge how to precisely control the self-assembly pathway in a desirable way by introducing abundant structural information into a limited molecular backbone. Here we disclose a strategy that directs the hierarchical self-assembly of sodium thioctate, a small molecule of biological origin, into a highly ordered supramolecular layered network. By combining the unique dynamic covalent ring-opening-polymerization of sodium thioctate and an evaporation-induced interfacial confinement effect, we precisely direct the dynamic supramolecular self-assembly of this simple small molecule in a scheduled hierarchical pathway, resulting in a layered structure with long-range order at both macroscopic and molecular scales, which is revealed by small-angle and wide-angle X-ray scattering technologies. The resulting supramolecular layers are found to be able to bind water molecules as structural water, which works as an interlayer lubricant to modulate the material properties, such as mechanical performance, self-healing capability, and actuating function. Analogous to many reversibly self-assembled biological systems, the highly dynamic polymeric network can be degraded into monomers and reformed by a water-mediated route, exhibiting full recyclability in a facile, mild, and environmentally friendly way. This approach for assembling commercial small molecules into structurally complex materials paves the way for low-cost functional supramolecular materials based on synthetically simple procedures.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.