ArticleAging cell2019
Rag1 immunodeficiency-induced early aging and senescence in zebrafish are dependent on chronic inflammation and oxidative stress.
Open access · goldAbstract read
In one paragraph
Article in Aging cell, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
27 citing papers in PubMed, 44 citations in OpenAlex.
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- Potential Probiotic Lacticaseibacillus rhamnosus NKU FL1-11 Prevents Aging-Related Oxidative Stress and Inflammation via mTOR and FoxO Signaling Pathways in Zebrafish.Probiotics and antimicrobial proteins · 2026Article
- Development of a Short Telomere Zebrafish Model for Accelerated Aging Research and Antiaging Drug Screening.Aging cell · 2025Article
- Establishment and application of a zebrafish model of Werner syndrome identifies sapanisertib as a potential antiaging drug.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Review
- In vivo multiscale analyses of spring viremia of carp virus (SVCV) infection: From model organism to target species.PLoS pathogens · 2024Article
- Influences of Stocking Density on Antioxidant Status, Nutrients Composition, and Lipid Metabolism in the Muscles ofAntioxidants (Basel, Switzerland) · 2024Article
- Navigating sex and sex roles: deciphering sex-biased gene expression in a species with sex-role reversal (Royal Society open science · 2024Article
- Senescence-associated ß-galactosidase staining over the lifespan differs in a short- and a long-lived fish species.European journal of histochemistry : EJH · 2024Article
- Inflammation in Development and Aging: Insights from the Zebrafish Model.International journal of molecular sciences · 2024Review
- Interwoven processes in fish development: microbial community succession and immune maturation.PeerJ · 2024Review
- The biological mechanism and emerging therapeutic interventions of liver aging.International journal of biological sciences · 2024Review
- Unraveling DNA Repair Processes In Vivo: Insights from Zebrafish Studies.International journal of molecular sciences · 2023Review
- Anti-inflammatory potential of baicalein combined with silk fibroin protein in a zebrafish model (Danio rerio).Biotechnology letters · 2023Article
- Zebrafish models of COVID-19.FEMS microbiology reviews · 2023Review
- Rag2Stem cell reports · 2022Article
- Senescence-Independent Anti-Inflammatory Activity of the Senolytic Drugs Dasatinib, Navitoclax, and Venetoclax in Zebrafish Models of Chronic Inflammation.International journal of molecular sciences · 2022Article
- Transcriptome analysis reveals the early resistance of zebrafish larvae to oxidative stress.Fish physiology and biochemistry · 2022Article
- Aging Activates the Immune System and Alters the Regenerative Capacity in the Zebrafish Heart.Cells · 2022Article
Corrections and comments
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Authors and funding
16 authors at 6 institutions in 1 country.
Beatriz NovoaInstituto de Investigaciones Marinas, Consejo Superior de Investigaciones Científicas (CSIC), Vigo, Spain.ORCID 0000-0003-4888-8419
Patricia PereiroInstituto de Investigaciones Marinas, Consejo Superior de Investigaciones Científicas (CSIC), Vigo, Spain.
Azucena López-MuñozDepartamento de Biología Celular e Histología, Facultad de Biología, Universidad de Murcia, IMIB-Arrixaca, Murcia, Spain.
Mónica VarelaInstituto de Investigaciones Marinas, Consejo Superior de Investigaciones Científicas (CSIC), Vigo, Spain.ORCID 0000-0003-0215-9173
Gabriel Forn-CuníInstituto de Investigaciones Marinas, Consejo Superior de Investigaciones Científicas (CSIC), Vigo, Spain.
Monique AnchelinGrupo de Telomerasa, Cáncer y Envejecimiento, Hospital Clínico Universitario Virgen de la Arrixaca, IMIB-Arrixaca, Murcia, Spain.
Sonia DiosInstituto de Investigaciones Marinas, Consejo Superior de Investigaciones Científicas (CSIC), Vigo, Spain.
Alejandro RomeroInstituto de Investigaciones Marinas, Consejo Superior de Investigaciones Científicas (CSIC), Vigo, Spain.
Alicia Martinez-LópezInstituto de Biología Molecular y Celular (IBMC), Universidad Miguel Hernández (UMH), Elche, Spain.
Regla María Medina-GaliInstituto de Biología Molecular y Celular (IBMC), Universidad Miguel Hernández (UMH), Elche, Spain.
Manuel ColladoInstituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Complexo Hospitalario Universitario de Santiago de Compostela (CHUS), SERGAS, Santiago de Compostela, Spain.ORCID 0000-0002-0330-0880
Julio CollDepartamento de Biotecnología, Instituto Nacional Investigación y Tecnología Agraria y Alimentaria (INIA), Madrid, Spain.
Amparo EstepaInstituto de Biología Molecular y Celular (IBMC), Universidad Miguel Hernández (UMH), Elche, Spain.
María Luisa CayuelaGrupo de Telomerasa, Cáncer y Envejecimiento, Hospital Clínico Universitario Virgen de la Arrixaca, IMIB-Arrixaca, Murcia, Spain.
Victoriano MuleroDepartamento de Biología Celular e Histología, Facultad de Biología, Universidad de Murcia, IMIB-Arrixaca, Murcia, Spain.ORCID 0000-0001-9527-0211
Antonio FiguerasInstituto de Investigaciones Marinas, Consejo Superior de Investigaciones Científicas (CSIC), Vigo, Spain.
Consejo Superior de Investigaciones Científicas · ESUniversitat de Miguel Hernández d'Elx · ESHospital Universitario Virgen de la Arrixaca · ESUniversidad de Murcia · ESInstituto de Investigación Sanitaria de Santiago · ESInstituto Nacional de Investigación y Tecnología Agraria y Alimentaria · ES
Funding
Agencia Estatal Consejo Superior de Investigaciones Científicas (CSIC) BIO2011-23400Agencia Estatal Consejo Superior de Investigaciones Científicas (CSIC) BIO2014-52655-RAgencia Estatal Consejo Superior de Investigaciones Científicas (CSIC) BIO2017-84702-RAgencia Estatal Consejo Superior de Investigaciones Científicas (CSIC) PI13/0234Consellería de Economía, Emprego e Industria (GAIN), Xunta de Galicia IN607B 2016/12Fondos Europeos de Desarrollo Regional/European Regional Development FundsFundación Séneca-Murcia 19400/PI/14Spanish Ministry of Economy and Competitiveness 51-C3-1-RSpanish Ministry of Economy and Competitiveness AGL2014-51773-C3Spanish Ministry of Economy and Competitiveness BIO2017-828Spanish Ministry of Economy and Competitiveness PIE 201230E057
Abstract
In mammals, recombination activating gene 1 (RAG1) plays a crucial role in adaptive immunity, generating a vast range of immunoglobulins. Rag1
Indexed as
AgingAnimalsCellular SenescenceChronic DiseaseHomeodomain ProteinsInflammationOxidative StressZebrafishHomeodomain ProteinsRAG-1 proteinagingDNA damageinflammationoxidative stressrag1senescence
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.