Evidence map›Paper›PMID 31348285›Full record

ArticleMedicine2019

Cryopreserved amniotic membrane and umbilical cord particulate matrix for partial rotator cuff tears: A case series.

J Freeland Ackley, Michael Kolosky, Danielle Gurin, Robert Hampton, Richard Masin, David Krahe

Open access · goldAbstract readEvaluation Study
In one paragraph

Article in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Use of biologics in rotator cuff disorders: Current concept review.Journal of clinical orthopaedics and trauma · 2021
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

J Freeland AckleyTwinsburg Family Health and Surgery Center, Twinsburg, OH.
Michael KoloskyTwinsburg Family Health and Surgery Center, Twinsburg, OH.
Danielle GurinTwinsburg Family Health and Surgery Center, Twinsburg, OH.
Robert HamptonTwinsburg Family Health and Surgery Center, Twinsburg, OH.
Richard MasinTwinsburg Family Health and Surgery Center, Twinsburg, OH.
David KraheTwinsburg Family Health and Surgery Center, Twinsburg, OH.
Seminary of the Southwest · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amniotic membrane (AM) and umbilical cord (UC) are well known to have anti-inflammatory properties and have been shown to promote healing in various orthopedic indications. This study investigated whether intra-articular injection of AM/UC particulate matrix promotes healing of partial rotator cuff tears (RCTs).A case series was performed on 10 patients that received injection of 50 mg AM/UC for partial RCTs that were refractory to conservative treatment. Outcomes included Penn Shoulder Score (PSS) questionnaire, range of motion examination, and magnetic resonance imaging (MRI) analysis before and at 6 months. Final MRI analysis was performed by a musculoskeletal radiologist in a blinded fashion.Average PSS score (out of 100) increased from 46.8 ± 23.7 at baseline to 82.0 ± 19.1 at 6 months. The average PSS sub-scores of pain, satisfaction, and function increased 78.4%, 37.1%, and 82.3% from baseline, respectively. The subject's range of motion was 77.9% at baseline and increased to 99.9% at 6-months. Follow-up MRI scans did not demonstrate any significant change in RCT size. No adverse events were noted.This small case series provides preliminary data for use of cryopreserved AM/UC particulate matrix in patients with refractory partial RCTs.

Indexed as

AmnionCryopreservationUmbilical CordAdultAgedBiological ProductsFemaleHumansInjections, Intra-ArticularMaleMiddle AgedRange of Motion, ArticularRetrospective StudiesRotator Cuff InjuriesShoulder JointTreatment OutcomeBiological Products

Identifiers

PMID31348285
PMCPMC6709267
OpenAlexW2964567605

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.