SynthesisMedicine2019
Systematic review with network meta-analysis: Diagnostic values of ultrasonography, computed tomography, and magnetic resonance imaging in patients with ischemic stroke.
Synthesis in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Efficacy and safety of magnetic resonance imaging- vs. computed tomography-guided reperfusion in acute ischemic stroke: a systematic review and meta-analysis.Frontiers in neurology · 2026Pooled it
- Imaging-validated correlates and implications of the pathophysiologic mechanisms of ageing-related cerebral large artery and small vessel diseases: a systematic review and meta-analysis.Behavioral and brain functions : BBF · 2025Pooled it
- Comparison of the diagnostic accuracy of shear wave elastography with transient elastography in adult nonalcoholic fatty liver disease: a systematic review and network meta-analysis of diagnostic test accuracy.Abdominal radiology (New York) · 2025Pooled it
- The comparison of MRI and CT protocol examination times for mechanical thrombectomy in acute ischemic stroke.Radiological physics and technology · 2025Article
- CT perfusion in the acute setting: a useful tool in the differential diagnosis of aphasic syndromes.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Observational
- Plasma brain-derived tau correlates with cerebral infarct volume.Journal of internal medicine · 2025Article
- Ischemic core detection threshold of computed tomography perfusion (CTP) in acute stroke.La Radiologia medica · 2024Article
- Predicting Mechanical Thrombectomy Outcome and Time Limit through ADC Value Analysis: A Comprehensive Clinical and Simulation Study Using Machine Learning.Diagnostics (Basel, Switzerland) · 2023Article
- Predictive Value of CT Perfusion in Hemorrhagic Transformation after Acute Ischemic Stroke: A Systematic Review and Meta-Analysis.Brain sciences · 2023Review
- A Short Review on Advances in Early Diagnosis and Treatment of Ischemic Stroke.Galen medical journal · 2023Review
- Association of concomitant headache with hypoperfusion in ischemic stroke: A multimodal CT-based study.Clinical and translational science · 2022Article
- CT- versus MRI-Based Imaging for Thrombolysis and Mechanical Thrombectomy in Ischemic Stroke: Analysis from the Austrian Stroke Registry.Journal of stroke · 2022Article
- A 78 Seconds Complete Brain MRI Examination in Ischemic Stroke: A Prospective Cohort Study.Journal of magnetic resonance imaging : JMRI · 2022Article
- Zero-TE MRI: principles and applications in the head and neck.The British journal of radiology · 2022Review
- Virtual monoenergetic dual-energy CT reconstructions at 80 keV are optimal non-contrast CT technique for early stroke detection.The neuroradiology journal · 2022Article
- Intelligent Algorithm-Based MRI Image Features for Evaluating the Effect of Nursing on Recovery of the Neurological Function of Patients with Acute Stroke.Contrast media & molecular imaging · 2022Article
- Value of 4D CT Angiography Combined with Whole Brain CT Perfusion Imaging Feature Analysis under Deep Learning in Imaging Examination of Acute Ischemic Stroke.Computational intelligence and neuroscience · 2022Article
- Investigating the role of susceptibility weighted imaging for assessment of ischemic penumbra with respect to Venus blood flow in ischemic stroke patients.International journal of physiology, pathophysiology and pharmacology · 2022Article
- Disruption of white matter integrity and its relationship with cognitive function in non-severe traumatic brain injury.Frontiers in neurology · 2022Article
- Monocytes carrying GFAP detect glioma, brain metastasis and ischaemic stroke, and predict glioblastoma survival.Brain communications · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectiveIschemic stroke is a foremost cause for disability and death worldwide. This study is conducted in order to compare the diagnostic values between transcranial Doppler ultrasound (ultrasonography), computed tomography (CT), and magnetic resonance imaging (MRI) in patients suffering from ischemic stroke by performing a network meta-analysis.
methodsWe made use of Cochrane Library, PubMed, and Embase in order to obtain literature and papers. The combination analysis of both direct and indirect evidence in terms of sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy was conducted so as to assess the odds ratios (ORs) and surface under the cumulative ranking curve (SUCRA) values of the seven different imaging methods. These imaging techniques include ultrasonography, computed tomography (traditional CT, computed tomography angiography [CTA], computed tomography perfusion [CTP]), and MRI (traditional MRI, diffusion-weighted imaging [DWI], magnetic resonance angiography), in order to properly diagnose ischemic stroke patients.
resultsThirteen eligible diagnostic trials were enrolled into this network meta-analysis. The results of the traditional meta-analysis showed that among CT methods, CTP showed higher sensitivity, NPV, and accuracy; among MRI methods, DWI had relatively higher sensitivity, NPV, and accuracy. The results of network meta-analysis showed that DWI had relatively higher sensitivity, NPV, and accuracy when compared with traditional CT, CTA, magnetic resonance angiography and traditional MRI. CTP showed higher SUCRA among CT methods while DWI showed higher SUCRA among MRI methods. A cluster analysis revealed that DWI had the highest diagnostic value in terms of sensitivity, PPV, NPV, and accuracy amongst the aforementioned seven imaging techniques.
conclusionThis network meta-analysis provides supporting evidence to the idea that DWI has a higher diagnostic value regarding ischemic stroke among MRI methods, and CTP has a poor diagnostic value among CT methods, which provide therapeutic considerations for Ischemic stroke intervention.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.