Evidence map›Paper›PMID 31347939›Full record

ArticleJournal of aerosol medicine and pulmonary drug delivery2019

Inhaled Submicron Particle Paclitaxel (NanoPac) Induces Tumor Regression and Immune Cell Infiltration in an Orthotopic Athymic Nude Rat Model of Non-Small Cell Lung Cancer.

James Verco, William Johnston, Michael Frost, Michael Baltezor, Philip J Kuehl, Anita Lopez, Andrew Gigliotti, Steven A Belinsky, Ronald Wolff, Gere diZerega

Open access · hybridAbstract readComparative Study
In one paragraph

Article in Journal of aerosol medicine and pulmonary drug delivery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Inhalable nanoparticle-based drug delivery system for non-small cell lung cancer therapy: promises and challenges.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2025
    Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Pharmacokinetics of inhaled nanotherapeutics for pulmonary delivery.Journal of controlled release : official journal of the Controlled Release Society · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

James VercoUS Biotest, Inc., San Luis Obispo, California.
William JohnstonUS Biotest, Inc., San Luis Obispo, California.
Michael FrostWestern Diagnostic Services Laboratory, Santa Maria, California.
Michael BaltezorCritiTech, Inc., Lawrence, Kansas.
Philip J KuehlLovelace Biomedical, Albuquerque, New Mexico.
Anita LopezLovelace Biomedical, Albuquerque, New Mexico.
Andrew GigliottiLovelace Biomedical, Albuquerque, New Mexico.
Steven A BelinskyLovelace Biomedical, Albuquerque, New Mexico.
Ronald WolffRK Wolff-Safety Consulting, Fort Myers, Florida.
Gere diZeregaUS Biotest, Inc., San Luis Obispo, California.
Lovelace Medical Center · USUS Biotest (United States) · USClinical Physiology Associates · USCritiTech (United States) · USUniversidade Federal de Santa Maria · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Administration, InhalationAlbuminsAnimalsAntineoplastic Agents, PhytogenicCarcinoma, Non-Small-Cell LungCell Line, TumorDose-Response Relationship, DrugHumansLung NeoplasmsMalePaclitaxelRatsRats, Nude130-nm albumin-bound paclitaxelAlbuminsAntineoplastic Agents, PhytogenicPaclitaxelaerosolathymic ratCalu-3chemotherapyinhaledjet nebulizerlung cancerNanoPacnon-small cell lung cancer (NSCLC)nude ratorthotopicpaclitaxelparticlepreclinicalrodentsubmicron

Identifiers

PMID31347939
PMCPMC6781259
OpenAlexW2964966462

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.