Evidence map›Paper›PMID 31347776›Full record

ArticlePediatric obesity2019

Unintentional error in formula preparation and its simulated impact on infant weight and adiposity.

Abby D Altazan, L Anne Gilmore, Juen Guo, David M Rosenberg, Danielle Toupo, Aaron Gowins, Jeffrey H Burton, Robbie A Beyl, Carson C Chow, Kevin D Hall and 1 more

Erratum issuedAbstract read
In one paragraph

Article in Pediatric obesity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. New frontiers in the measurement of energy metabolism.American journal of physiology. Endocrinology and metabolism · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Abby D AltazanReproductive Endocrinology and Women's Health, Pennington Biomedical Research Center, Baton Rouge, Louisiana, United States.
L Anne GilmoreReproductive Endocrinology and Women's Health, Pennington Biomedical Research Center, Baton Rouge, Louisiana, United States.
Juen GuoNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health (NIH), Bethesda, Maryland, United States.
David M RosenbergNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health (NIH), Bethesda, Maryland, United States.
Danielle ToupoNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health (NIH), Bethesda, Maryland, United States.
Aaron GowinsNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health (NIH), Bethesda, Maryland, United States.
Jeffrey H BurtonReproductive Endocrinology and Women's Health, Pennington Biomedical Research Center, Baton Rouge, Louisiana, United States.
Robbie A BeylReproductive Endocrinology and Women's Health, Pennington Biomedical Research Center, Baton Rouge, Louisiana, United States.
Carson C ChowNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health (NIH), Bethesda, Maryland, United States.
Kevin D HallNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health (NIH), Bethesda, Maryland, United States.
Leanne M RedmanReproductive Endocrinology and Women's Health, Pennington Biomedical Research Center, Baton Rouge, Louisiana, United States.ORCID 0000-0002-7267-7374

Funding

Tracking & Evaluation CoreU54GM104940 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Peter Todd Katzmarzyk · 2012 to 2026
$69.1M
Research BaseP30DK072476 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Sujoy Ghosh · 2005 to 2026
$26.5M
Training in Obesity ResearchT32DK064584 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI CORBY K MARTIN, Christopher D Morrison · 2003 to 2026
$5.3M
Computational modeling of human metabolism, body weight and compositionZIADK013036 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI HALL, KEVIN · 2009 to 2024
$3.6M
Modeling and data analysis of obesity, insulin resistance, and diabetesZIADK013022 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI CHOW, CARSON · 2009 to 2025
$2.8M
Intramural NIH HHS ZIA DK013036NIDDK NIH HHS P30 DK072476NIDDK NIH HHS T32 DK064584NIGMS NIH HHS U54 GM104940NIH HHS 1U54GM104940NIH HHS P30DK072476
6 · The paper itself

Abstract

backgroundAccelerated weight gain in infancy is a public health issue and is likely due to feeding behaviours.

objectivesTo test the accuracy of individuals to dispense infant formula as compared with recommended serving sizes and to estimate the effect of dispensing inaccuracy on infant growth.

methodsFifty-three adults dispensed infant formula powder for three servings of 2, 4, 6, and 8 fl oz bottles, in random order. The weight of dispensed infant formula powder was compared with the recommended serving size weight on the nutrition label. A novel mathematical model was used to estimate the impact of formula dispensing on infant weight and adiposity.

resultsNineteen percent of bottles (20 of 636) prepared contained the recommended amount of infant formula powder. Three percent were underdispensed, and 78% of bottles were overdispensed, resulting in 11% additional infant formula powder. Mathematical modelling feeding 11% above energy requirements exclusively for 6 months for male and female infants suggested infants at the 50th percentile for weight at birth would reach the 75th percentile with increased adiposity by 6 months.

conclusionsInaccurate measurement of infant formula powder and overdispensing, which is highly prevalent, specifically, may contribute to rapid weight gain and increased adiposity in formula-fed infants.

Indexed as

AdiposityBody WeightInfant FormulaAdolescentAdultAgedAged, 80 and overCross-Sectional StudiesFemaleHumansInfantInfant, NewbornInfant Nutritional Physiological PhenomenaMaleMiddle AgedModels, Theoreticalfeedinginfant formulainfant growthmathematical modelling

Identifiers

PMID31347776
PMCPMC6834868

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.