Evidence map›Paper›PMID 31347281›Full record

ArticleThe clinical respiratory journal2019

Increased pulmonary artery diameter is associated with reduced FEV

Rafael E de la Hoz, Yunho Jeon, Anthony P Reeves, Raúl San José Estépar, Xiaoyu Liu, John T Doucette, Juan C Celedón, Anna Nolan

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The clinical respiratory journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03295279 (Pulmonary Diseases in WTC Workers), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03295279 enrolling by invitationnot on this map

Pulmonary Diseases in WTC Workers: Symptoms, Function, and Chest CT Correlates

TypeobservationalSponsorIcahn School of Medicine at Mount SinaiRan2012 to 2027Enrolled2,122ConditionsChronic Airway Disease, Interstitial Lung Disease, Lung Cancer
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Dynamic Metabolic Risk Profiling of World Trade Center Lung Disease: A Longitudinal Cohort Study.American journal of respiratory and critical care medicine · 2021
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rafael E de la HozDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, New York.ORCID https://orcid.org/0000-0002-8949-9279
Yunho JeonDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, New York.ORCID https://orcid.org/0000-0002-2923-3284
Anthony P ReevesSchool of Electrical and Computer Engineering, Cornell University, Ithaca, New York.ORCID https://orcid.org/0000-0002-1451-3080
Raúl San José EstéparDepartment of Radiology, Brigham and Women's Hospital, Boston, Massachusetts.ORCID https://orcid.org/0000-0002-3677-1996
Xiaoyu LiuDepartment of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, New York.ORCID https://orcid.org/0000-0002-6528-0213
John T DoucetteDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, New York.ORCID https://orcid.org/0000-0001-8985-0367
Juan C CeledónDivision of Pediatric Pulmonary Medicine, Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, Pennsylvania.ORCID https://orcid.org/0000-0002-6139-5320
Anna NolanDepartment of Medicine, New York University School of Medicine, New York, New York.ORCID https://orcid.org/0000-0002-0631-1171

Funding

Pulmonary Diseases in WTC Workers: Symptoms, Function, and Chest CT CorrelatesU01OH010401 · OH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI DE LA HOZ, RAFAEL E. · 2012 to 2025
$7.3M
Metabolomics of World Trade Center-Lung Injury: Biomarker Validation, Longitudinal Assessment and Dietary InterventionU01OH011300 · OH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI NOLAN, ANNA · 2017 to 2025
$4.8M
RAGE Mediates LPA Induced Pulmonary InflammationR01HL119326 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI NOLAN, ANNA · 2015 to 2019
$2.1M
Chronic Obstructive Pulmonary Disease in WTC Workers - Diagnoses and TransitionsU01OH011697 · OH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI DE LA HOZ, RAFAEL E. · 2018 to 2025
$1.9M
CDC/NIOSH 200-2017-93325NHLBI NIH HHS R01 HL119326NIOSH CDC HHS U01 OH010401NIOSH CDC HHS U01 OH011300NIOSH CDC HHS U01 OH011697
6 · The paper itself

Abstract

rationaleOccupational exposures at the WTC site after September 11, 2001 have been associated with several presumably inflammatory lower airway diseases. Pulmonary arterial enlargement, as suggested by an increased ratio of the diameter of the pulmonary artery to the diameter of the aorta (PAAr) has been reported as a computed tomographic (CT) scan marker of adverse respiratory health outcomes, including WTC-related disease. In this study, we sought to utilize a novel quantitative CT (QCT) measurement of PAAr to test the hypothesis that an increased ratio is associated with FEV

methodsIn a group of 1,180 WTC workers and volunteers, we examined whether FEV

resultsUnadjusted analyses showed a statistically significant association of FEV

conclusionsIn WTC workers, FEV

Indexed as

AdultBronchodilator AgentsFemaleForced Expiratory VolumeHumansMaleMiddle AgedNew YorkOccupational ExposurePulmonary ArteryPulmonary Disease, Chronic ObstructiveRespiratory Function TestsSeptember 11 Terrorist AttacksSmoke Inhalation InjuryStress Disorders, Post-TraumaticTomography, X-Ray ComputedBronchodilator Agents2001computer-assisted image processingmultidetector computed tomographyoccupational medicinepulmonary arterysmoke inhalation injuryspirometryWorld Trade Center attack

Identifiers

PMID31347281
PMCPMC6783324

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.