Evidence map›Paper›PMID 31347204›Full record

ArticleDrug and alcohol review2019

Medical and non-medical cannabis use and risk of prescription opioid use disorder: Findings from propensity score matching.

Di Liang, Mark S Wallace, Yuyan Shi

Abstract read
In one paragraph

Article in Drug and alcohol review, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Di LiangDepartment of Family Medicine and Public Health, University of California San Diego, La Jolla, USA.
Mark S WallaceDepartment of Anesthesiology, University of California San Diego, La Jolla, USA.
Yuyan ShiDepartment of Family Medicine and Public Health, University of California San Diego, La Jolla, USA.ORCID 0000-0001-9293-0659

Funding

Neighborhood Physical, Economic, and Socioeconomic Environment In Relation to Marijuana Use and DisorderR01DA042290 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SHI, YUYAN · 2017 to 2020
$2.6M
NIDA NIH HHS R01 DA042290
6 · The paper itself

Abstract

INTRODUCTION AND

aimsPrevious research suggested that cannabis use was associated with increased risks of prescription opioid misuse and use disorder. This study examined whether these associations differed by cannabis use purpose. DESIGN AND

methodsThis is a secondary analysis of cross-sectional surveys with propensity score matching. Medical cannabis users (N = 1295), cannabis dual users with both medical and non-medical purposes (N = 707) and non-medical cannabis users (N = 18 666) were compared with cannabis non-users (N = 57 196) in the pooled 2013-2016 US nationally representative National Survey on Drug Use and Health. Propensity score models were applied to match cannabis non-users to cannabis users with different purposes with respect to potential confounders in individual socioeconomic characteristics, other substance use disorders and health conditions. In a matched sample, logistic regressions were used to assess associations.

resultsPropensity score matching considerably improved the balance of the potential confounders between cannabis non-users and users. In a matched sample, non-medical cannabis use was associated with increased risks of prescription opioid misuse (OR = 3.15, 95%CI: 2.89-3.44) and use disorder (OR = 2.52, 95%CI: 2.06-3.10). Cannabis dual use and medical cannabis use were associated with increased risks of prescription opioid misuse (OR = 2.55, 95%CI: 1.78-3.65; OR = 2.15, 95%CI: 1.58-2.91, respectively), but they were not associated with prescription opioid use disorder. DISCUSSION AND

conclusionsMedical and non-medical cannabis use both were both associated with increased risks of prescription opioid misuse. Medical cannabis use, however, was not associated with prescription opioid use disorder, and non-medical cannabis was. There appeared to be differential associations between cannabis use and prescription opioid use disorder by cannabis use purpose.

Indexed as

AdultAgedAnalgesics, OpioidCross-Sectional StudiesFemaleHumansMaleMarijuana SmokingMarijuana UseMedical MarijuanaMiddle AgedOpioid-Related DisordersPrescription Drug MisuseAnalgesics, OpioidMedical Marijuanamedical cannabisopioid misuseopioid use disorderpropensity score matching

Identifiers

PMID31347204
PMCPMC6774839

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.