Evidence map›Paper›PMID 31346796›Full record

ArticleEJNMMI research2019

Preclinical investigations and first-in-human application of

Cristina Müller, Aviral Singh, Christoph A Umbricht, Harshad R Kulkarni, Karl Johnston, Martina Benešová, Stefan Senftleben, Dirk Müller, Christiaan Vermeulen, Roger Schibli and 3 more

Open access · goldAbstract read
In one paragraph

Article in EJNMMI research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 72 citations in OpenAlex.

  1. Tetrazine-Inorganic chemistry frontiers · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Advances in PSMA-Targeted Radionuclide Therapeutics.Current treatment options in oncology · 2025
    Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. Preclinical Evaluation of [Molecules (Basel, Switzerland) · 2023
    Article
  16. Article
  17. Review
  18. Review
  19. First-in-Humans Application ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2021
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 4 countries.

Cristina MüllerCenter for Radiopharmaceutical Sciences ETH-PSI-USZ, Paul Scherrer Institute, 5232, Villigen-PSI, Switzerland. cristina.mueller@psi.ch.ORCID http://orcid.org/0000-0001-9357-9688
Aviral SinghTheranostics Center for Molecular Radiotherapy and Precision Oncology, ENETS Center of Excellence, Zentralklinik Bad Berka, Robert-Koch-Allee 9, 99437, Bad Berka, Germany.
Christoph A UmbrichtCenter for Radiopharmaceutical Sciences ETH-PSI-USZ, Paul Scherrer Institute, 5232, Villigen-PSI, Switzerland.
Harshad R KulkarniTheranostics Center for Molecular Radiotherapy and Precision Oncology, ENETS Center of Excellence, Zentralklinik Bad Berka, Robert-Koch-Allee 9, 99437, Bad Berka, Germany.
Karl JohnstonCERN, Geneva, Switzerland.
Martina BenešováCenter for Radiopharmaceutical Sciences ETH-PSI-USZ, Paul Scherrer Institute, 5232, Villigen-PSI, Switzerland.
Stefan SenftlebenTheranostics Center for Molecular Radiotherapy and Precision Oncology, ENETS Center of Excellence, Zentralklinik Bad Berka, Robert-Koch-Allee 9, 99437, Bad Berka, Germany.
Dirk MüllerTheranostics Center for Molecular Radiotherapy and Precision Oncology, ENETS Center of Excellence, Zentralklinik Bad Berka, Robert-Koch-Allee 9, 99437, Bad Berka, Germany.
Christiaan VermeulenCenter for Radiopharmaceutical Sciences ETH-PSI-USZ, Paul Scherrer Institute, 5232, Villigen-PSI, Switzerland.
Roger SchibliCenter for Radiopharmaceutical Sciences ETH-PSI-USZ, Paul Scherrer Institute, 5232, Villigen-PSI, Switzerland.
Ulli KösterInstitut Laue-Langevin, Grenoble, France.
Nicholas P van der MeulenCenter for Radiopharmaceutical Sciences ETH-PSI-USZ, Paul Scherrer Institute, 5232, Villigen-PSI, Switzerland.
Richard P BaumTheranostics Center for Molecular Radiotherapy and Precision Oncology, ENETS Center of Excellence, Zentralklinik Bad Berka, Robert-Koch-Allee 9, 99437, Bad Berka, Germany.
Paul Scherrer Institute · CHZentralklinik Bad Berka · DEEuropean Organization for Nuclear Research · CHInstitut Laue-Langevin · FRMaastricht University · NL

Funding

ENSAR2 654002
6 · The paper itself

Abstract

backgroundFor almost a decade, terbium radioisotopes have been explored for their potential theragnostic application in nuclear medicine:

results

conclusionsThe results of this study demonstrate the successful preparation and preclinical testing of

Indexed as

152TbPET/CT imagingProstate cancerPSMA-617TerbiumTheragnostics

Identifiers

PMID31346796
PMCPMC6658632
OpenAlexW2964218694

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.