Evidence map›Paper›PMID 31346575›Full record

ReviewAnnals of gastroenterological surgery2019

Cutting-edge strategies for borderline resectable pancreatic cancer.

Rajesh S Shinde, Manish Bhandare, Vikram Chaudhari, Shailesh V Shrikhande

Abstract readReview
In one paragraph

Review in Annals of gastroenterological surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rajesh S ShindeGI & HPB Service Department of Surgical Oncology Tata Memorial Hospital Mumbai Maharashtra India.ORCID https://orcid.org/0000-0001-9478-8676
Manish BhandareGI & HPB Service Department of Surgical Oncology Tata Memorial Hospital Mumbai Maharashtra India.
Vikram ChaudhariGI & HPB Service Department of Surgical Oncology Tata Memorial Hospital Mumbai Maharashtra India.
Shailesh V ShrikhandeGI & HPB Service Department of Surgical Oncology Tata Memorial Hospital Mumbai Maharashtra India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Worldwide, pancreatic ductal adenocarcinoma (PDAC) accounts for more than 400 000 deaths every year, being the 12th most common cancer and the seventh most frequent cause of death from cancer. Regardless of the advances in diagnosis and treatment, PDAC continues to have dismal outcomes and fewer than 25% of patients survive for 1 year. In the absence of metastatic disease, radical surgery remains the most important factor for improving survival and possibly offer cure. However, approximately 80% of patients cannot be offered surgery owing to locally advanced or metastatic disease at presentation. At presentation, only 10%-20% patients are eligible for resection, 30%-40% are unresectable/locally advanced and 50%-60% are metastatic. One promising development in recent years has been the inclusion of a new subgroup within the locally advanced tumors of borderline resectable pancreatic cancer (BRPC) comprising approximately 5%-10% of the total patient population. Although its exact definition has been refined over the past few years depending on the vascular involvement around the tumor, the term was initially proposed for tumors that are at a high risk of having margin positivity after resection. Various treatment approaches are still evolving for this entity. Herein, we reviewed the current status of different treatment modalities for BRPC.

Indexed as

borderlineborderline resectable pancreatic cancerpancreatic cancerpancreaticoduodenectomy

Identifiers

PMID31346575
PMCPMC6635681

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.