Evidence map›Paper›PMID 31346561›Full record

ArticleJBMR plus2019

Predictors of Imminent Risk of Nonvertebral Fracture in Older, High-Risk Women: The Framingham Osteoporosis Study.

Marian T Hannan, Derek Weycker, Robert R McLean, Shivani Sahni, Rebecca Bornheimer, Richard Barron, Thomas G Travison, Douglas P Kiel

Abstract read
In one paragraph

Article in JBMR plus, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Update of the fracture risk prediction tool FRAX: a systematic review of potential cohorts and analysis plan.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022
    Pooled it
  3. Pooled it
  4. Screening for Osteoporosis in Nonagenarians: A Scoping Review.Journal of the American Geriatrics Society · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. One- and 2-year incidence of osteoporotic fracture: a multi-cohort observational study using routinely collected real-world data.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022
    Observational
  11. Review
  12. Short time horizons for fracture prediction tools: time for a rethink.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021
    Article
  13. Review
  14. Determinants of imminent fracture risk in postmenopausal women with osteoporosis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2020
    Article
  15. Grip strength in men and women aged 50-79 years is associated with non-vertebral osteoporotic fracture during 15 years follow-up: The Tromsø Study 1994-1995.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marian T HannanInstitute for Aging Research Hebrew SeniorLife Department of Medicine Beth Israel Deaconess Medical Center, and Harvard Medical School Boston MA USA.
Derek WeyckerPolicy Analysis Inc. (PAI) Brookline MA USA.
Robert R McLeanCorrona, LLC, Waltham, MA, USA, and Institute for Aging Research Hebrew SeniorLife Boston MA USA.
Shivani SahniInstitute for Aging Research Hebrew SeniorLife Department of Medicine Beth Israel Deaconess Medical Center, and Harvard Medical School Boston MA USA.
Rebecca BornheimerPolicy Analysis Inc. (PAI) Brookline MA USA.
Richard BarronAmgen Thousand Oaks CA USA.
Thomas G TravisonInstitute for Aging Research Hebrew SeniorLife Department of Medicine Beth Israel Deaconess Medical Center, and Harvard Medical School Boston MA USA.
Douglas P KielInstitute for Aging Research Hebrew SeniorLife Department of Medicine Beth Israel Deaconess Medical Center, and Harvard Medical School Boston MA USA.

Funding

RISK FACTORS FOR VERTEBRAL FRACTURE AND BONE LOSSR01AR041398 · NIAMS · RHODE ISLAND HOSPITAL (PROVIDENCE, RI) · PI KIEL, DOUGLAS P. · 1991 to 2025
$16.1M
The Gut Microbiome and Bone MicroarchitectureR01AR061445 · NIAMS · HEBREW REHABILITATION CENTER FOR AGED · PI KIEL, DOUGLAS P. · 2012 to 2021
$8.9M
NHLBI NIH HHS HHSN268201500001CNHLBI NIH HHS HHSN268201500001INIAMS NIH HHS R01 AR041398NIAMS NIH HHS R01 AR061445
6 · The paper itself

Abstract

Osteoporosis treatment decisions are often based solely on BMD or on 10-year fracture risk; little is known about factors increasing imminent fracture risk. Understanding factors contributing to imminent risk of fracture is potentially useful for personalizing therapy, especially among those at high risk. Our aim was to identify predictors of nonvertebral fracture for 1- and 2-year periods in women at high risk for fracture. The Framingham Osteoporosis Study cohort included 1470 women (contributing 2778 observations), aged ≥65 years with BMD hip

Indexed as

COHORT STUDYIMMINENT FRACTURENON‐VERTEBRAL FRACTUREOLDER ADULTSRISK PREDICTION

Identifiers

PMID31346561
PMCPMC6636767

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.