Evidence map›Paper›PMID 31346521›Full record

Trial reportBioMed research international2019

Use of Cumulative Live Birth Rate per Total Number of Embryos to Calculate the Success of IVF in Consecutive IVF Cycles in Women Aged ≥35 Years.

Meng Zhang, Tao Bu, Haiqing Tian, Xia Li, Duolao Wang, Xiaohui Wan, Qingli Wang, Xinmin Mao, Xiaolin La

Abstract readClinical Trial
In one paragraph

Trial report in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Meng ZhangXinjiang Medical University, the First Affiliated Hospital, Urumqi, Xinjiang, China.
Tao BuXinjiang Medical University, the First Affiliated Hospital, Urumqi, Xinjiang, China.
Haiqing TianXinjiang Medical University, the First Affiliated Hospital, Urumqi, Xinjiang, China.
Xia LiXinjiang Medical University, the First Affiliated Hospital, Urumqi, Xinjiang, China.
Duolao WangLiverpool School of Tropical Medicine, Liverpool L3 5QA, UK.
Xiaohui WanXinjiang Medical University, the First Affiliated Hospital, Urumqi, Xinjiang, China.
Qingli WangXinjiang Medical University, the First Affiliated Hospital, Urumqi, Xinjiang, China.
Xinmin MaoXinjiang Medical University, the First Affiliated Hospital, Urumqi, Xinjiang, China.
Xiaolin LaXinjiang Medical University, the First Affiliated Hospital, Urumqi, Xinjiang, China.ORCID https://orcid.org/0000-0002-9793-2853

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe use of cumulative live birth rate (CLBR) per ovarian stimulation cycle is proving to be an accurate method to calculate the success of IVF; however, the cycle outcome is closely associated with the number of embryos transferred (ET). Our aim was to report CLBR after IVF according to the number of embryos required to achieve a live birth in women aged ≥35 years, considering age, body mass index (BMI), and ethnicity.

methodsWe conducted a retrospective cohort study including 1344 patients who underwent IVF between January 2013 and June 2016 at the First Affiliated Hospital of Xinjiang Medical University. The cumulative probability of live birth for each couple was estimated using the Kaplan-Meier method, and survival curves were compared according to age, BMI, and ethnicity using the log-rank test.

resultsCLBR increased rapidly from 1 to 5 ETs, moderately from 6 to 10 ETs, and slowly thereafter. CLBR was significantly different across 4 categories based on BMI as well as across those based on age; low CLBR was significantly associated with the age of ≥42 years and obesity.

conclusionThe association between CLBR and number of ET provides realistic and precise information regarding the success of IVF and can be applied to guide clinicians and patients.

Indexed as

Embryo TransferFertilization in VitroLive BirthOvulation InductionAdultAge FactorsFemaleHumansMiddle AgedRetrospective Studies

Identifiers

PMID31346521
PMCPMC6617928

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.