ArticleMolecular autism2019
Integrated genetic and methylomic analyses identify shared biology between autism and autistic traits.
Article in Molecular autism, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Meta-analysis of epigenome-wide associations between DNA methylation at birth and childhood cognitive skills.Molecular psychiatry · 2022Pooled it
- Intolerance of Uncertainty Mediates the Relationship Between Autistic Traits and a Propensity for Deliberation.Journal of autism and developmental disorders · 2025Article
- An epigenome-wide association study in the case-control study to explore early development identifies differential DNA methylation near ZFP57 as associated with autistic traits.Journal of neurodevelopmental disorders · 2025Article
- Superior temporal sulcus folding, functional network connectivity, and autistic-like traits in a non-clinical population.Molecular autism · 2024Article
- Modelling the overlap and divergence of autistic and schizotypal traits on hippocampal subfield volumes and regional cerebral blood flow.Molecular psychiatry · 2024Article
- Can the "female protective effect" liability threshold model explain sex differences in autism spectrum disorder?Neuron · 2022Review
- Bioinformatics analysis of genomic and immune infiltration patterns in autism spectrum disorder.Annals of translational medicine · 2022Article
- Epigenetic profiling of social communication trajectories and co-occurring mental health problems: a prospective, methylome-wide association study.Development and psychopathology · 2022Article
- Maternal diabetes-mediated RORA suppression in mice contributes to autism-like offspring through inhibition of aromatase.Communications biology · 2022Article
- Autistic traits are associated with faster pace of aging: Evidence from the Dunedin study at age 45.Autism research : official journal of the International Society for Autism Research · 2021Article
- Biological implications of genetic variations in autism spectrum disorders from genomics studies.Bioscience reports · 2021Review
- Sperm DNA methylation epimutation biomarker for paternal offspring autism susceptibility.Clinical epigenetics · 2021Article
- An Exploratory Study of a Dimensional Assessment of the Diagnostic Criteria for Autism.Journal of autism and developmental disorders · 2020Article
- Phenotypic Subtyping and Re-Analysis of Existing Methylation Data from Autistic Probands in Simplex Families Reveal ASD Subtype-Associated Differentially Methylated Genes and Biological Functions.International journal of molecular sciences · 2020Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Previous studies have identified differences in DNA methylation in autistic individuals compared to neurotypical individuals. Yet, it is unclear if this extends to autistic traits-subclinical manifestation of autism features in the general population. Here, we investigate the association between DNA methylation at birth (cord blood), and scores on the Social and Communication Disorders Checklist (SCDC), a measure of autistic traits, in 701 8-year-olds, by conducting a methylome-wide association study (MWAS). We did not identify significant CpGs associated with SCDC. The most significant CpG site was cg14379490, on chromosome 9 (MWAS beta = - 1.78 ± 0.35,
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.