Evidence map›Paper›PMID 31346352›Full record

ArticleHereditary cancer in clinical practice2019

Somatic variants of potential clinical significance in the tumors of

Lela Buckingham, Rachel Mitchell, Mark Maienschein-Cline, Stefan Green, Vincent Hong Hu, Melody Cobleigh, Jacob Rotmensch, Kelly Burgess, Lydia Usha

Open access · goldAbstract read
In one paragraph

Article in Hereditary cancer in clinical practice, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Lela Buckingham1Department of Pathology, Rush University Medical Center, Chicago, IL USA.ORCID 0000-0002-2735-0946
Rachel Mitchell3Tennessee Oncology, Shelbyville, TN USA.
Mark Maienschein-Cline4University of Illinois at Chicago Research Resources Center, Chicago, IL USA.
Stefan Green4University of Illinois at Chicago Research Resources Center, Chicago, IL USA.
Vincent Hong Hu4University of Illinois at Chicago Research Resources Center, Chicago, IL USA.
Melody Cobleigh2Rush Cancer Institute, Rush University Medical Center, Chicago, IL USA.
Jacob Rotmensch2Rush Cancer Institute, Rush University Medical Center, Chicago, IL USA.
Kelly Burgess2Rush Cancer Institute, Rush University Medical Center, Chicago, IL USA.
Lydia Usha2Rush Cancer Institute, Rush University Medical Center, Chicago, IL USA.
Rush University Medical Center · USUniversity of Illinois Chicago · USTennessee College of Applied Technology - Shelbyville · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

methodsTo assess the nature and potential clinical significance of somatic variants in

resultsNone of the familial

conclusionsAlthough limited by a small sample size, these results support a role of selected somatic variants and epigenetic mechanisms in the development of tumors in

Indexed as

HBOCNGSPhenocopySomatic mutations

Identifiers

PMID31346352
PMCPMC6636136
OpenAlexW2962194246

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.