Evidence map›Paper›PMID 31346326›Full record

ArticleContrast media & molecular imaging2019

Synthesis and Preclinical Evaluation of the Fibrin-Binding Cyclic Peptide

Yin Zhang, Lijuan Wang, Sirui Yu, Kongzhen Hu, Shun Huang, Youcai Li, Hubing Wu, Hongsheng Li, Quanshi Wang

Open access · hybridAbstract read
In one paragraph

Article in Contrast media & molecular imaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yin ZhangPET Center, Nanfang Hospital, Southern Medical University, Guangzhou, China.ORCID 0000-0003-4129-5629
Lijuan WangPET Center, Nanfang Hospital, Southern Medical University, Guangzhou, China.ORCID 0000-0002-7728-9282
Sirui YuPET Center, Nanfang Hospital, Southern Medical University, Guangzhou, China.ORCID 0000-0002-1647-0395
Kongzhen HuPET Center, Nanfang Hospital, Southern Medical University, Guangzhou, China.ORCID 0000-0002-7889-9576
Shun HuangPET Center, Nanfang Hospital, Southern Medical University, Guangzhou, China.ORCID 0000-0002-0576-9308
Youcai LiPET/CT Center, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.ORCID 0000-0001-8259-7637
Hubing WuPET Center, Nanfang Hospital, Southern Medical University, Guangzhou, China.ORCID 0000-0002-7546-5430
Hongsheng LiPET Center, Nanfang Hospital, Southern Medical University, Guangzhou, China.ORCID 0000-0003-1040-4108
Quanshi WangPET Center, Nanfang Hospital, Southern Medical University, Guangzhou, China.ORCID 0000-0003-2003-3603
Nanfang Hospital · CNFirst Affiliated Hospital of Guangzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Cys-Arg-Glu-Lys-Ala (CREKA) is a pentapeptide which can target fibrin-fibronectin complexes. Our previous study has built a probe called iCREKA which was based on CREKA and has proved the feasibility and specificity of iCREKA by the fluorescence experiment. The purpose of this study is to achieve the Methods: CREKA, LP, and iCREKA were labeled by the Al Results: Conclusions: The novel CREKA-based probe

Indexed as

Positron-Emission TomographyAnimalsCell Line, TumorFibrinFibronectinsFluorine RadioisotopesGlioblastomaHeterograftsHumansMiceOligopeptidesPeptides, CyclicTissue Distributioncysteinyl-arginyl-glutamyl-lysyl-alanylFibrinFibronectinsFluorine RadioisotopesOligopeptidesPeptides, Cyclic

Identifiers

PMID31346326
PMCPMC6620859
OpenAlexW2953889680

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.