Evidence map›Paper›PMID 31346209›Full record

ArticleScientific reports2019

Septins organize endoplasmic reticulum-plasma membrane junctions for STIM1-ORAI1 calcium signalling.

Zachary B Katz, Chen Zhang, Ariel Quintana, Björn F Lillemeier, Patrick G Hogan

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Orai1 is an Entotic CaAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
  5. Super resolution microscopy analysis reveals increased Orai1 activity in asthma and cystic fibrosis lungs.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2023
    Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. PIPCell calcium · 2021
    Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. Visualization of integrin molecules by fluorescence imaging and techniques.Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al · 2021
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Zachary B KatzDivision of Signalling and Gene Expression, La Jolla Institute for Immunology, La Jolla, CA, 92037, USA.
Chen ZhangDivision of Signalling and Gene Expression, La Jolla Institute for Immunology, La Jolla, CA, 92037, USA.ORCID http://orcid.org/0000-0001-7148-8881
Ariel QuintanaDivision of Signalling and Gene Expression, La Jolla Institute for Immunology, La Jolla, CA, 92037, USA.
Björn F LillemeierNOMIS Center for Immunobiology and Microbial Pathogenesis & Waitt Advanced Biophotonics Center, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA. blillemeier@salk.edu.
Patrick G HoganDivision of Signalling and Gene Expression, La Jolla Institute for Immunology, La Jolla, CA, 92037, USA. phogan@lji.org.
La Jolla Institute for Immunology · USSalk Institute for Biological Studies · US

Funding

Viral Vector Core (VVC)P30CA014195 · NCI · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI Reuben Shaw · 1985 to 2026
$82.8M
Salk Institute Cancer Training GrantT32CA009370 · NCI · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI Diana Clare Hargreaves, Jan Karlseder · 1986 to 2026
$8.6M
NFAT, bZIP proteins, and transcriptional programs in lymphocytesR01AI109842 · NIAID · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI Patrick Hogan, Anjana Rao · 2014 to 2026
$8.6M
STIM-ORAI signaling and other calcium influx pathways in lymphocytesR01AI084167 · NIAID · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI HOGAN, PATRICK · 2009 to 2019
$4.9M
Training in Immunological MechanismsT32AI125179 · NIAID · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI CROFT, MICHAEL · 2016 to 2025
$3.1M
Nanoscale regulation of store-operated calcium entry through STIM-ORAI signallingR01GM110397 · NIGMS · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI HOGAN, PATRICK, LILLEMEIER, BJOERN F · 2014 to 2017
$1.4M
NCI NIH HHS P30 CA014195NCI NIH HHS T32 CA009370NIAID NIH HHS R01 AI084167NIAID NIH HHS R01 AI109842NIAID NIH HHS T32 AI125179NIGMS NIH HHS R01 GM110397
6 · The paper itself

Abstract

ORAI1 Ca

Indexed as

CalciumCalcium SignalingCell MembraneEndoplasmic ReticulumHeLa CellsHumansORAI1 ProteinSeptinsStromal Interaction Molecule 1CalciumORAI1 ProteinSeptinsStromal Interaction Molecule 1

Identifiers

PMID31346209
PMCPMC6658532
OpenAlexW2964161587

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.