ArticleNature communications2019
3D-structured supports create complete data sets for electron crystallography.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed.
- Semi-automated MicroED system unveils multiple polymorphs in fish-derived guanine crystals.Acta crystallographica. Section C, Structural chemistry · 2026Article
- Single-cell structural biology with intracellular electron crystallography.Nature communications · 2026Article
- Direct from the seed: an atomic resolution protein structure by ab initio MicroED.Nature communications · 2026Article
- Strategies for mitigating radiation damage and improving data completeness in 3D electron diffraction of protein crystals.Acta crystallographica. Section D, Structural biology · 2026Article
- Limiting the effects of radiation damage in MicroED through dose selection during data processing.Acta crystallographica. Section D, Structural biology · 2025Article
- Unit-cell parameters determination from a set of independent electron diffraction zonal patterns.Acta crystallographica. Section A, Foundations and advances · 2025Article
- Cross-sectional analysis of gut microbiome diversity with progression of Alzheimer's disease.Bioinformation · 2025Article
- Mastering the art of sectioning: a comprehensive guide to slide-microtome technology and histological applications.Frontiers in veterinary science · 2025Review
- Reaching the potential of electron diffraction.Cell reports. Physical science · 2024Article
- 3D Nanocrystallography and the Imperfect Molecular Lattice.Annual review of physical chemistry · 2024Review
- Scaling up cryo-EM for biology and chemistry: The journey from niche technology to mainstream method.Structure (London, England : 1993) · 2023Review
- Quantitative three-dimensional local order analysis of nanomaterials through electron diffraction.Nature communications · 2023Article
- 3D electron diffraction for structure determination of small-molecule nanocrystals: A possible breakthrough for the pharmaceutical industry.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2022Review
- 3D Electron Diffraction for Chemical Analysis: Instrumentation Developments and Innovative Applications.Chemical reviews · 2021Review
- Establishing electron diffraction in chemical crystallography.Nature reviews. Chemistry · 2021Review
- Serial Electron Diffraction Data Processing With diffractem and CrystFEL.Frontiers in molecular biosciences · 2021Article
- Fragment-based determination of a proteinase K structure from MicroED data using ARCIMBOLDO_SHREDDER.Acta crystallographica. Section D, Structural biology · 2020Article
- Scanning electron microscopy as a method for sample visualization in protein X-ray crystallography.IUCrJ · 2020Article
- Serial protein crystallography in an electron microscope.Nature communications · 2020Article
- MicroED methodology and development.Structural dynamics (Melville, N.Y.) · 2020Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
3D electron crystallography has recently attracted much attention due to its complementarity to X-ray crystallography in determining the structure of compounds from submicrometre sized crystals. A big obstacle lies in obtaining complete data, required for accurate structure determination. Many crystals have a preferred orientation on conventional, flat sample supports. This systematically shades some part of the sample and prevents the collection of complete data, even when several data sets are combined. We introduce two types of three-dimensional sample supports that enable the collection of complete data sets. In the first approach the carbon layer forms coils on the sample support. The second approach is based on chaotic nylon fibres. Both types of grids disrupt the preferred orientation as we demonstrate with a well suited crystal type of MFI-type zeolites. The easy-to-obtain three-dimensional sample supports have different features, ensuring a broad spectrum of applications for these 3D support grids.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.