Evidence map›Paper›PMID 31345326›Full record

ArticleClinics in dermatology

Aging and the treatment of basal cell carcinoma.

Shreya Sreekantaswamy, Justin Endo, Amy Chen, Daniel Butler, Lily Morrison, Eleni Linos

Abstract read
In one paragraph

Article in Clinics in dermatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Nanotechnology as a Promising Method in the Treatment of Skin Cancer.International journal of molecular sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shreya SreekantaswamyUniversity of Utah School of Medicine, Salt Lake City, Utah, USA.
Justin EndoUniversity of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Amy ChenUniversity of California, San Francisco School of Medicine, San Francisco, California, USA.
Daniel ButlerUniversity of California, San Francisco School of Medicine, San Francisco, California, USA.
Lily MorrisonStanford University School of Medicine, Stanford, California, USA.
Eleni LinosStanford University School of Medicine, Stanford, California, USA. Electronic address: linos@stanford.edu.

Funding

Patient Oriented Research in Vulnerable Populations with Skin DiseaseK24AR075060 · NIAMS · STANFORD UNIVERSITY · PI Eleni Linos · 2019 to 2026
$1.6M
Involving older adults in decision making for skin cancerK76AG054631 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LINOS, ELENI · 2016 to 2018
$644k
NIAMS NIH HHS K24 AR075060NIA NIH HHS K76 AG054631
6 · The paper itself

Abstract

Basal cell carcinoma (BCC) is the most commonly diagnosed type of skin cancer. BCCs are especially prevalent in the elderly population, given their association with cumulative sun exposure and other risk factors. In this contribution, we outline geriatric concepts related to the care of older adults with BCCs. We describe how a patient's life expectancy can be estimated and combined with tumor characteristics to determine lag time to benefit, a concept to better understand whether patients will experience the efficacy of a treatment within their life span. We also review the possibility of current BCC overdiagnosis and summarize the effectiveness, benefits, and risks of common treatments for BCCs, noting that all treatment modalities have special considerations when administered to older adults. In particular, nonsurgical treatments might be preferable for older adults with a limited life expectancy. Ultimately, we argue that the decision of whether and how to treat a BCC should be the result of shared decision-making between the provider and the patient and take into account not only tumor characteristics, but also patient values and preferences.

Indexed as

AgedAge FactorsAgingBasal Cell CarcinomaHumansRisk AssessmentSkin NeoplasmsTreatment Outcome

Identifiers

PMID31345326
PMCPMC6952217

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.