ArticleActa veterinaria Scandinavica2019
Acute phase response in bovine coronavirus positive post-weaned calves with diarrhea.
Article in Acta veterinaria Scandinavica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 27 citations in OpenAlex.
- Molecular characterization of bovine viral diarrhea virus and host genetic immune and biochemical responses in diarrheic buffalo calves.Scientific reports · 2026Article
- Bovine Coronavirus in diarrheic pre-weaned calves in Egypt: prevalence, risk factors, and the associated biochemical alterations.Tropical animal health and production · 2025Article
- Evaluation of bovine coronavirus in Korean native calves challenged through different inoculation routes.Veterinary research · 2024Article
- Acute phase protein concentration in pharyngeal swabs from clinically healthy commercial dairy calves.Acta veterinaria Scandinavica · 2023Article
- Seroprevalence and Risk Factors for Bovine Coronavirus Infection among Dairy Cattle and Water Buffalo in Campania Region, Southern Italy.Animals : an open access journal from MDPI · 2023Article
- Literature Review: Coinfection in Young Ruminant Livestock-Pathogens (Basel, Switzerland) · 2022Review
- Bovine Coronavirus Infects the Respiratory Tract of Cattle Challenged Intranasally.Frontiers in veterinary science · 2022Article
- Risk factors for morbidity in 1- to 9-day-old dairy calves following caustic paste disbudding.JDS communications · 2021Article
- Alteration of the gut microbiota in post-weaned calves following recovery from bovine coronavirus-mediated diarrhea.Journal of animal science and technology · 2021Article
- Changes in serum protein electrophoresis profiles and acute phase proteins in calves with diarrhea.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2021Article
- Extreme Genomic CpG Deficiency in SARS-CoV-2 and Evasion of Host Antiviral Defense.Molecular biology and evolution · 2020Article
- Ultrasensitive haptoglobin biomarker detection based on amplified chemiluminescence of magnetite nanoparticles.Journal of nanobiotechnology · 2020Article
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
Abstract
Bovine coronavirus (BCoV) is associated with severe diarrhea in calves, winter dysentery in adult cattle, and respiratory diseases in cattle of all ages. This study aimed to investigate the relationship between white blood cell counts and haptoglobin (Hp) and serum amyloid A (SAA) levels in post-weaned calves with diarrhea caused by BCoV and those that recovered from diarrhea. Blood and fecal samples were collected twice from the same animals; 17 post-weaned calves with diarrhea (first) and 15 post-weaned calves that recovered from diarrhea (second). Real-time polymerase chain reaction revealed that all 17 fecal samples from post-weaned calves with diarrhea and one out of 15 from diarrhea-recovered calves were positive for BCoV and negative for Cryptosporidium spp., Escherichia coli K99, Salmonella spp., bovine rotavirus, and bovine viral diarrhea virus. No Eimeria oocysts were detected using the flotation method. In comparison with post-weaned calves with diarrhea, in diarrhea-recovered calves, the lymphocyte count was significantly higher (P = 0.018), and the monocyte count was significantly lower (P = 0.001); however, the number of monocytes was still high. Post-weaned calves with diarrhea had a significantly higher Hp concentration (P < 0.001) compared with diarrhea-recovered calves. The results indicated that increased Hp concentration and monocytosis but not SAA may be associated with diarrhea caused by BCoV. The present study suggests that the monitoring of Hp concentration and monocyte count is useful in the diagnosis of post-weaned calves with diarrhea caused by BCoV in this field.
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