Evidence map›Paper›PMID 31345192›Full record

ArticleBMC urology2019

Comparison of various continence definitions in a large group of patients undergoing radical prostatectomy: a multicentre, prospective study.

Sigrun Holze, Meinhard Mende, Karl V Healy, Norbert Koehler, Lutz Gansera, Michael C Truss, Udo Rebmann, Stephan Degener, Jens-Uwe Stolzenburg

Open access · goldAbstract readComparative StudyMulticenter Study
In one paragraph

Article in BMC urology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 7 pooled it
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 7 syntheses or guidelines pooled it, 66 citations in OpenAlex.

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  16. Anxiety, depression, urinary continence, and sexuality in patients undergoing radical prostatectomy: preliminary findings.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Sigrun HolzeDepartment of Urology, University of Leipzig, Liebigstr. 20, 04103, Leipzig, Germany. sigrun.holze@medizin.uni-leipzig.de.ORCID http://orcid.org/0000-0001-9091-5244
Meinhard MendeCoordination Centre for Clinical Trials, University of Leipzig, Härtelstr. 16-18, 04107, Leipzig, Germany.
Karl V HealyDepartment of Urology, University of Leipzig, Liebigstr. 20, 04103, Leipzig, Germany.
Norbert KoehlerDepartment of Medical Psychology and Medical Sociology, University of Leipzig, Philipp-Rosenthal-Str. 55, 04103, Leipzig, Germany.
Lutz GanseraDepartment of Medical Psychology and Medical Sociology, University of Leipzig, Philipp-Rosenthal-Str. 55, 04103, Leipzig, Germany.
Michael C TrussDepartment of Urology, Klinikum Dortmund, Beurhausstr. 40, 44137, Dortmund, Germany.
Udo RebmannDepartment of Urology, Diakonissenkrankenhaus Dessau, Gropiusallee 3, 06846, Dessau, Germany.
Stephan DegenerDepartment of Urology, Helios Klinikum Wuppertal, Heusnerstr. 40, 42283, Wuppertal, Germany.
Jens-Uwe StolzenburgDepartment of Urology, University of Leipzig, Liebigstr. 20, 04103, Leipzig, Germany.
Leipzig University · DEDiakonissenkrankenhaus · DEHelios Universitätsklinikum Wuppertal · DEKlinikum Dortmund · DEUniversity Hospital Leipzig · DE

Funding

Deutsche Krebshilfe IN-1260910
6 · The paper itself

Abstract

backgroundDue to the usage of various measurement methods and definitions, comparing continence rates after radical prostatectomy is a challenging task. This study compares continence rates based on different methods and aims to identify the definition for continence which agrees best with the patients' subjective assessment of continence. Additionally, continence was controlled for multiple influencing factors.

methodsThis prospective multicentre study was carried out in seven hospitals throughout Germany. Before and at 3, 6, and 12 months after surgery self-reporting questionnaires were completed and returned by 329 (84.4%) of 390 eligible patients. The questionnaires were independently evaluated and analysed by a third party. Association of continence with demographic, operative, and tumour factors in an ongoing comprehensive prostate cancer database was evaluated.

resultsThe continence rate drops substantially for patients undergoing radical prostatectomy but increases again with time. Concrete numbers vary considerably depending on definition - 44% at 3 months and 68% at 12 months after surgery (0 pads) vs. 71 and 90% (0-1 pads). Significant confounding variables regarding continence rate are nerve-sparing procedure, categorized Gleason score, rehabilitative cure treatment, and pelvic floor training. The definition of 0 pads for continence coincides greater than 0-1 pads with the patients' self-assessment of being continent.

conclusionA standardized definition for continence would be desirable, as it is one of the most important preconditions to guarantee sound comparison of continence rates. Since there are enough other factors that make comparison difficult, we suggest using the definition of "0 pads". It is easily measured objectively, leaves no room for interpretation, and agrees best with the patients' self-assessment.

Indexed as

AgedAged, 80 and overFollow-Up StudiesHumansLongitudinal StudiesMaleMiddle AgedPostoperative ComplicationsProspective StudiesProstatectomyProstatic NeoplasmsUrinary Incontinence

Identifiers

PMID31345192
PMCPMC6659208
OpenAlexW2964907113

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.