ReviewBMC pediatrics2019
Successful conservative treatment of intestinal perforation in VLBW and ELBW neonates: a single centre case series and review of the literature.
Review in BMC pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 15 citations in OpenAlex.
- Application Effect of Colostrum Oral Immunotherapy in the Early Stage of Mechanical Ventilation for Very Low Birth Weight Preterm Infants.Journal of multidisciplinary healthcare · 2026Article
- Case report: Catastrophic event: neonatal gastric perforation and complication of capillary leak syndrome.Frontiers in pediatrics · 2023Article
- Distinctive clinical features of spontaneous pneumoperitoneum in neonates: A retrospective analysis.World journal of clinical cases · 2022Article
- Outcomes of laparotomy in preterm infants with extremely low operative weight (< 1000 g).Pediatric surgery international · 2022Article
- Clinical features and outcomes of bowel perforation in primary pediatric gastrointestinal lymphoma.BMC pediatrics · 2021Article
- Using machine learning analysis to assist in differentiating between necrotizing enterocolitis and spontaneous intestinal perforation: A novel predictive analytic tool.Journal of pediatric surgery · 2021Article
- Blood group AB increases risk for surgical necrotizing enterocolitis and focal intestinal perforation in preterm infants with very low birth weight.Scientific reports · 2021Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe current standard treatment of neonates with intestinal perforation is surgery. However, the mortality rate after surgical treatment for intestinal perforation is very high for very low birth weight (VLBW) and extremely low birth weight (ELBW) neonates. In this review, conservative treatment of pneumoperitoneum among VLBW and ELBW neonates is investigated.
methodsBetween January 2015 and December 2017, data from all of the VLBW and ELBW neonates with pneumoperitoneum who survived without surgical treatment were collected from Shenzhen Maternity and Child Healthcare Hospital in Guangdong, China. Twenty-two neonates with birth weight less than 1500 g were diagnosed with pneumoperitoneum. Following careful evaluation and discussion, eleven were treated conservatively and this was successful in eight. Details of the eight neonates including birth weight, gestational age, gender, risk factors, time of the perforation, treatment and prognosis were retrospectively recorded. A literature review was performed of previously reported cases that had used conservative treatment.
resultsThe median gestational age and birth weight of the eight neonates were 27
conclusionsConservative treatment with careful surveillance may be a practical choice for the VLBW and ELBW neonates with intestinal perforation. Further studies are needed for confirmation.
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Registered trials
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