Evidence map›Paper›PMID 31345178›Full record

ArticleBMC pregnancy and childbirth2019

Induction of labor and postpartum blood loss.

Romana Brun, Emilian Spoerri, Leonhard Schäffer, Roland Zimmermann, Christian Haslinger

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMC pregnancy and childbirth, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06010368 (The Effect of Intramyometrial Tranexamic Acid Versus Intramyometrial Oxytocin in Reducing Blood Loss During and After Elective Cesarean Section in Term Primigravida), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06010368 phase3not yet recruitingnot on this mapstarted 2024, after this paper: background citation

The Effect of Intramyometrial Tranexamic Acid Versus Intramyometrial Oxytocin in Reducing Blood Loss During and After Elective Cesarean Section in Term Primigravida: A Double-blinded, Randomized, Comparative-placebo Trial

TypeinterventionalSponsorCairo UniversityRan2024 to 2026Enrolled150ConditionsCesarean Section Complications, Tranexamic Acid, Oxytocin, Post Partum HemorrhageArmsTranexamic acid injection, Oxytocin
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Romana BrunDivision of Obstetrics, University Hospital Zurich, Frauenklinikstrasse 10, 8091, Zurich, Switzerland.
Emilian SpoerriUniversity of Zurich, Zurich, Switzerland.
Leonhard SchäfferDivision of Obstetrics, Kantonsspital Baden, Baden, Switzerland.
Roland ZimmermannDivision of Obstetrics, University Hospital Zurich, Frauenklinikstrasse 10, 8091, Zurich, Switzerland.
Christian HaslingerDivision of Obstetrics, University Hospital Zurich, Frauenklinikstrasse 10, 8091, Zurich, Switzerland. christian.haslinger@usz.ch.ORCID http://orcid.org/0000-0003-3344-9480
University Hospital of Zurich · CHKantonsspital Baden · CHUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo analyze blood loss after delivery in women with induction of labor compared to women with spontaneous onset of labor.

methodsIn this secondary analysis of a prospective cohort study investigating postpartum hemorrhage, 965 deliveries were analyzed including 380 women with induction of labor (39%) between 2015 and 2016. Primary outcome parameters were rate of postpartum hemorrhage, estimated blood loss and post-partum decrease in hemoglobin.

resultsRates of postpartum hemorrhage and estimated blood loss were not significantly different in women with induction of labor. Women with induction of labor had a significantly reduced decrease in hemoglobin after delivery. In the multivariate linear regression analysis, induction of labor remained associated with reduced decrease in hemoglobin. Secondary maternal and neonatal outcomes were unaffected.

conclusionsInduction of labor is not associated with increased blood loss after delivery and should not be regarded as a risk factor for postpartum hemorrhage.

Indexed as

AdultFemaleHumansLabor, InducedPostpartum HemorrhagePregnancyPregnancy OutcomeProspective StudiesRisk FactorsDelta hemoglobinInduction of laborPostpartum blood lossPostpartum hemorrhageSpontaneous onset of labor

Identifiers

PMID31345178
PMCPMC6659310
OpenAlexW2963036627

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.