ArticleInternational journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group2019
Increased uptake of doxorubicin by cells undergoing heat stress does not explain its synergistic cytotoxicity with hyperthermia.
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Article in International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 29 citations in OpenAlex.
- Hyperthermia-induced cytotoxicity and modulation of PD-L1 and MHC-I expression in human non-small cell lung cancer cell lines.Experimental physiology · 2025Article
- Magnetic hyperthermia therapy enhances the chemoradiosensitivity of glioblastoma.Scientific reports · 2025Article
- Article
- MONITORING PERFUSION-BASED CONVECTION IN CANCER TUMOR TISSUE UNDERGOING NANOPARTICLE HEATING BY ANALYZING TEMPERATURE RESPONSES TO TRANSIENT PULSED HEATING.Proceedings of the ASME Summer Heat Transfer Conference. ASME Summer Heat Transfer Conference · 2023Article
- Metal-enriched HSP90 nanoinhibitor overcomes heat resistance in hyperthermic intraperitoneal chemotherapy used for peritoneal metastases.Molecular cancer · 2023Article
- Photothermal Properties of IR-780-Based Nanoparticles Depend on Nanocarrier Design: A Comparative Study on Synthetic Liposomes and Cell Membrane and Hybrid Biomimetic Vesicles.Pharmaceutics · 2023Article
- HYPER: pre-clinical device for spatially-confined magnetic particle hyperthermia.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2023Article
- Current Challenges in Image-Guided Magnetic Hyperthermia Therapy for Liver Cancer.Nanomaterials (Basel, Switzerland) · 2022Review
- Ultrasound Triggers Hypericin Activation Leading to Multifaceted Anticancer Activity.Pharmaceutics · 2022Article
- Hyperthermia Enhances Efficacy of Chemotherapeutic Agents in Pancreatic Cancer Cell Lines.Biomolecules · 2022Article
- Hyperthermia Enhances Doxorubicin Therapeutic Efficacy against A375 and MNT-1 Melanoma Cells.International journal of molecular sciences · 2021Article
- Sublethal hyperthermia enhances anticancer activity of doxorubicin in chronically hypoxic HepG2 cells through ROS-dependent mechanism.Bioscience reports · 2021Article
- The impact of hyperthermic intraperitoneal chemotherapy and cytoreductive surgery on clinical outcomes and quality of life of patients with peritoneal carcinomatosis.Contemporary oncology (Poznan, Poland) · 2021Article
- The effect of injected dose on localized tumor accumulation and cardiac uptake of doxorubicin in a Vx2 rabbit tumor model using MR-HIFU mild hyperthermia and thermosensitive liposomes.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2020Article
- Image-Guided Radiofrequency Hyperthermia (RFH)-Enhanced Direct Chemotherapy of Hepatic Tumors: The Underlying Biomolecular Mechanisms.Frontiers in oncology · 2020Article
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Authors and funding
16 authors at 2 institutions in 2 countries.
Anirudh Sharmaa Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine , Baltimore , MD , USA.
Sanem Özayrala Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine , Baltimore , MD , USA.
Julia S Casertoa Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine , Baltimore , MD , USA.
Rosemarie Ten Cateb Department of Radiation Oncology, Amsterdam University Medical Centers, University of Amsterdam , Amsterdam , Amsterdam , The Netherlands.
Nicole M Andersc Department of Oncology, Johns Hopkins University School of Medicine , Baltimore , MD , USA.
James D Barnetta Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine , Baltimore , MD , USA.
Sri Kamal Kandalaa Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine , Baltimore , MD , USA.
Elizabeth Hendersona Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine , Baltimore , MD , USA.
Jacqueline Stewarta Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine , Baltimore , MD , USA.
Eleni Liapie Department of Radiology and Radiological Sciences, Johns Hopkins Hospital , Baltimore , MD , USA.
Michelle A Rudekc Department of Oncology, Johns Hopkins University School of Medicine , Baltimore , MD , USA.
Nicolaas A P Frankenb Department of Radiation Oncology, Amsterdam University Medical Centers, University of Amsterdam , Amsterdam , Amsterdam , The Netherlands.ORCID 0000-0002-5522-9406
Arlene L Oeia Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine , Baltimore , MD , USA.ORCID 0000-0002-6936-1934
Preethi Korangatha Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine , Baltimore , MD , USA.ORCID 0000-0002-6623-493X
Fred Bunza Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine , Baltimore , MD , USA.
Robert Ivkova Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine , Baltimore , MD , USA.ORCID 0000-0002-2930-5276
Johns Hopkins University · USAmsterdam University Medical Centers · NL
Funding
Translational Research Central ServicesP30CA006973 · NCI · JOHNS HOPKINS UNIVERSITY · PI WILLIAM George NELSON · 1985 to 2026
$208.6MInstitute for Clinical and Translational ResearchUL1TR001079 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2013 to 2017
$60.1MTumor Antigens for Individual Signatures and TherapyP50CA062924 · NCI · JOHNS HOPKINS UNIVERSITY · PI JAFFEE, ELIZABETH M. · 1993 to 2022
$54.6MValidationU54CA151838 · NCI · JOHNS HOPKINS UNIVERSITY · PI POMPER, MARTIN G, SEARSON, PETER C · 2010 to 2014
$11.9MEnhancing Liver Cancer Treatment With Image-Guided Magnetic HyperthermiaR01CA194574 · NCI · JOHNS HOPKINS UNIVERSITY · PI IVKOV, ROBERT · 2015 to 2019
$3.2MHopkinsPREP: Research, Community, Professional Training and Personal GrowthR25GM109441 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI WILSON, KATHERINE L · 2015 to 2024
$3.2MUPLC with Tandem MS for Sensitive Quantitative Analysis of Small MoleculesS10RR026824 · NCRR · JOHNS HOPKINS UNIVERSITY · PI RUDEK, MICHELLE A · 2010 to 2010
$429kImage-guided thermo-chemoembolization for treatment of liver cancerR21CA161626 · NCI · JOHNS HOPKINS UNIVERSITY · PI LIAPI, ELENI A. · 2012 to 2013
$377kNCATS NIH HHS UL1 TR001079NCI NIH HHS P30 CA006973NCI NIH HHS P50 CA062924NCI NIH HHS R01 CA194574NCI NIH HHS R21 CA161626NCI NIH HHS U54 CA151838NCRR NIH HHS S10 RR026824NIGMS NIH HHS R25 GM109441
Abstract
PubMed holds no abstract for this paper.
Indexed as
Hot TemperatureAntibiotics, AntineoplasticBiological TransportCell DeathCell Line, TumorDoxorubicinHumansAntibiotics, AntineoplasticDoxorubicinchemotherapycolorectal cancerdoxorubicinHyperthermiathermal dose
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.