SynthesisJournal of cellular physiology2019
The role of pretreatment prognostic nutritional index in esophageal cancer: A meta-analysis.
Synthesis in Journal of cellular physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 8 of them syntheses that pooled it.
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Who cites it
38 citing papers in PubMed, 8 syntheses or guidelines pooled it.
- Prognostic Nutritional Index and Cancer Prognostic Outcomes: An Umbrella Review of Systematic Reviews and Meta-analyses of Observational Studies.Advances in nutrition (Bethesda, Md.) · 2026Pooled it
- Association between malnutrition diagnosed by different screening and assessment tools and clinical outcomes: an umbrella review.Frontiers in nutrition · 2025Pooled it
- Prognostic significance of prognostic nutritional index in patients with head and neck squamous cell carcinoma.Frontiers in immunology · 2025Pooled it
- Pretreatment prognostic nutritional index as a prognostic marker in head and neck cancer: a systematic review and meta-analysis.Scientific reports · 2021Pooled it
- Pooled it
- The prognostic role of prognostic nutritional index in nasopharyngeal carcinoma: A systematic review and meta-analysis.International journal of clinical oncology · 2021Pooled it
- Pooled it
- The role of pretreatment prognostic nutritional index in esophageal cancer: A meta-analysis.Journal of cellular physiology · 2019Pooled it
- Beyond tumor biology: can host nutritional status refine prediction of early recurrence after pancreatic cancer surgery?Gland surgery · 2026Article
- Prognostic nutritional index is associated with severe postoperative complications after neoadjuvant immunochemotherapy for esophageal squamous cell carcinoma: a retrospective cohort study with threshold effect analysis.Journal of cardiothoracic surgery · 2026Article
- Risk factors for postoperative intensive care unit admission after minimally invasive esophagectomy following neoadjuvant chemoimmunotherapy in patients with esophageal squamous cell carcinoma: a retrospective cohort study.Frontiers in oncology · 2026Article
- Association of perioperative cholesterol depletion with anastomotic leak after esophagectomy for cancer: a retrospective study.Journal of thoracic disease · 2025Article
- Patient background and laboratory variables associated with the efficacy of nivolumab after chemoradiotherapy in esophageal squamous cell carcinoma.Molecular and clinical oncology · 2025Article
- Validated nomograms for non-metastatic colorectal cancer prognosis prediction: a population-based study.Frontiers in oncology · 2025Article
- Prognostic Nutritional Index is a valuable preoperative prognostic biomarker in Mexican patients surgically intervened on gastrointestinal stromal tumors: a retrospective cohort study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- A nomogram combining neutrophil to lymphocyte ratio (NLR) and prognostic nutritional index (PNI) to predict distant metastasis in gastric cancer.Scientific reports · 2024Article
- Comparison of the prognostic value of eight nutrition-related tools in older patients with cancer: A prospective study.The journal of nutrition, health & aging · 2024Article
- Clinical-radiomics nomogram for the risk prediction of esophageal fistula in patients with esophageal squamous cell carcinoma treated with intensity-modulated radiation therapy or volumetric-modulated arc therapy.Journal of thoracic disease · 2024Article
- Molecular Targets and Mechanisms of Hedyotis diffusa Willd. for Esophageal Adenocarcinoma Treatment Based on Network Pharmacology and Weighted Gene Co-expression Network Analysis.Current drug targets · 2024Article
- Risk factors for unplanned intensive care unit admission after esophagectomy: a retrospective cohort study of 628 patients with esophageal cancer.Frontiers in oncology · 2024Article
Corrections and comments
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Authors and funding
5 authors.
Funding
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Abstract
Clinicopathological characteristics and prognosis of esophageal cancer (EC) patients with decreased prognostic nutritional index (PNI) have not been well investigated. So, we conducted this meta-analysis. We performed comprehensive research in PubMed, Embase, and Cochrane databases. The effect size was hazard ratio (HR) with 95% confidence interval (CI) for overall survival (OS) and cancer-specific survival (CSS). The pooled odds ratio (OR) with 95% CI were used to assess the association between PNI and clinicopathological features. A total of 3,425 EC patients were included in the present meta-analysis. Male patients, advanced age, higher tumor stage, and lymph node metastases were associated with reduced PNI level (OR = 1.40, 95% CI: 1.10-1.79; OR = 1.35, 95% CI: 1.10-1.66; OR = 2.37, 95% CI: 1.91-2.94; OR = 1.63, 95% CI: 1.04-2.56). And, the EC patients with decreased PNI held a worse OS and CSS compared with those who carried a higher PNI (HR = 1.29, 95% CI: 1.10-1.50; HR = 2.53, 95% CI: 1.15-5.57). This meta-analysis demonstrated PNI level was associated with tumor stage and lymph nodes metastases and was an independent prognostic factor in EC.
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