Evidence map›Paper›PMID 31344905›Full record

ArticleMolecules (Basel, Switzerland)2019

The Antiglycoxidative Ability of Selected Phenolic Compounds-An In Vitro Study.

Agnieszka Piwowar, Anna Rorbach-Dolata, Izabela Fecka

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Effects of Water-Ethanol Extracts from FourPharmaceuticals (Basel, Switzerland) · 2023
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  7. Neuroprotective Effect of WhiteFoods (Basel, Switzerland) · 2023
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  8. Anti-Glucotoxicity Effect of PhytoconstituentsInternational journal of molecular sciences · 2023
    Review
  9. Antioxidant and Antiglycation Effects ofMolecules (Basel, Switzerland) · 2022
    Article
  10. Vanillic Acid Inhibited the Induced Glycation Using In Vitro and In Vivo Models.Evidence-based complementary and alternative medicine : eCAM · 2022
    Article
  11. Effect ofPlants (Basel, Switzerland) · 2021
    Article
  12. Article
  13. Review
  14. Article
  15. Glycation Inhibition of Bovine Serum Albumin by Extracts ofAvicenna journal of medical biotechnology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Agnieszka PiwowarDepartment of Toxicology, Faculty of Pharmacy, Wroclaw Medical University, Borowska Str. 211, 50-556 Wrocław, Poland. agnieszka.piwowar@umed.wroc.pl.
Anna Rorbach-DolataDepartment of Toxicology, Faculty of Pharmacy, Wroclaw Medical University, Borowska Str. 211, 50-556 Wrocław, Poland.
Izabela FeckaDepartment of Pharmacognosy and Herbal Medicines, Faculty of Pharmacy, Wroclaw Medical University, Borowska Str. 211A, 50-556 Wrocław, Poland.

Funding

Uniwersytet Medyczny im. Piastów Slaskich we Wroclawiu ST-958 and ST.D110.16.008.
6 · The paper itself

Abstract

Hyperglycemia and oxidative stress may be observed in different diseases as important factors connected with their development. They often occur simultaneously and are considered together as one process: Glycoxidation. This can influence the function or structure of many macromolecules, for example albumin, by changing their physiological properties. This disturbs the homeostasis of the organism, so the search for natural compounds able to inhibit the glycoxidation process is a current and important issue. The aim of this study was the examination of the antiglycoxidative capacity of 16 selected phenolic compounds, belonging to three phenolic groups, as potential therapeutic agents. Their antiglycoxidative ability, in two concentrations (2 and 20 µM), were examined by in vitro study. The inhibition of the formation of both glycoxidative products (advanced glycation end products (AGEs) and advanced oxidation protein products (AOPPs)) were assayed. Stronger antiglycoxidative action toward the formation of both AOPPs and AGEs was observed for homoprotocatechuic and ferulic acids in lower concentrations, as well as catechin, quercetin, and 8-

Indexed as

Advanced Oxidation Protein ProductsAntioxidantsGlycation End Products, AdvancedHypoglycemic AgentsMolecular StructureMolecular WeightOxidation-ReductionPhenolsStructure-Activity RelationshipAdvanced Oxidation Protein ProductsAntioxidantsGlycation End Products, AdvancedHypoglycemic AgentsPhenolsAGEsantiglycoxidative potentialAOPPsglycoxidationphenolic compounds

Identifiers

PMID31344905
PMCPMC6696369

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.