Evidence map›Paper›PMID 31344881›Full record

ReviewInternational journal of molecular sciences2019

Synthesis and Application of Silver Nanoparticles (Ag NPs) for the Prevention of Infection in Healthcare Workers.

Shingo Nakamura, Masahiro Sato, Yoko Sato, Naoko Ando, Tomohiro Takayama, Masanori Fujita, Masayuki Ishihara

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed, 2 pooled it
13.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

76 citing papers in PubMed, 2 syntheses or guidelines pooled it, 256 citations in OpenAlex.

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16 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Shingo NakamuraDivision of Biomedical Engineering, National Defense Medical College Research Institute, Saitama 359-8513, Japan. snaka@ndmc.ac.jp.ORCID 0000-0001-6084-0958
Masahiro SatoSection of Gene Expression Regulation, Frontier Science Research Center, Kagoshima University, Kagoshima 890-8544, Japan.ORCID 0000-0003-1334-2950
Yoko SatoDivision of Biomedical Engineering, National Defense Medical College Research Institute, Saitama 359-8513, Japan.ORCID 0000-0001-8123-5191
Naoko AndoDivision of Biomedical Engineering, National Defense Medical College Research Institute, Saitama 359-8513, Japan.
Tomohiro TakayamaDepartment of Oral and Maxillofacial Surgery, National Defense Medical College Hospital, Saitama 359-8513, Japan.
Masanori FujitaDivision of Environmental Medicine, National Defense Medical College Research Institute, Saitama 359-8513, Japan.
Masayuki IshiharaDivision of Biomedical Engineering, National Defense Medical College Research Institute, Saitama 359-8513, Japan.
National Defense Medical College · JPKagoshima University · JPNational Defense Medical College Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Silver is easily available and is known to have microbicidal effect; moreover, it does not impose any adverse effects on the human body. The microbicidal effect is mainly due to silver ions, which have a wide antibacterial spectrum. Furthermore, the development of multidrug-resistant bacteria, as in the case of antibiotics, is less likely. Silver ions bind to halide ions, such as chloride, and precipitate; therefore, when used directly, their microbicidal activity is shortened. To overcome this issue, silver nanoparticles (Ag NPs) have been recently synthesized and frequently used as microbicidal agents that release silver ions from particle surface. Depending on the specific surface area of the nanoparticles, silver ions are released with high efficiency. In addition to their bactericidal activity, small Ag NPs (<10 nm in diameter) affect viruses although the microbicidal effect of silver mass is weak. Because of their characteristics, Ag NPs are useful countermeasures against infectious diseases, which constitute a major issue in the medical field. Thus, medical tools coated with Ag NPs are being developed. This review outlines the synthesis and utilization of Ag NPs in the medical field, focusing on environment-friendly synthesis and the suppression of infections in healthcare workers (HCWs).

Indexed as

Anti-Bacterial AgentsAnti-Infective AgentsChloridesDrug Resistance, Multiple, BacterialHealth PersonnelHumansInfectionsIonsMetal NanoparticlesSilverAnti-Bacterial AgentsAnti-Infective AgentsChloridesIonsSilverantiviral propertycytotoxicityhealthcare workers (HCWs)medical applicationmicrobicidal propertysilver nanoparticles (Ag NPs)

Identifiers

PMID31344881
PMCPMC6695748
OpenAlexW2963039258

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.