Evidence map›Paper›PMID 31344802›Full record

ArticleMolecules (Basel, Switzerland)2019

Development and Optimization of Alpha-Pinene-Loaded Solid Lipid Nanoparticles (SLN) Using Experimental Factorial Design and Dispersion Analysis.

Aleksandra Zielińska, Nuno R Ferreira, Alessandra Durazzo, Massimo Lucarini, Nicola Cicero, Soukaina El Mamouni, Amélia M Silva, Izabela Nowak, Antonello Santini, Eliana B Souto

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

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  16. Potassium Alum [KAl(SOHeliyon · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Aleksandra ZielińskaDepartment of Pharmaceutical Technology, Faculty of Pharmacy, University of Coimbra (FFUC), Pólo das Ciências da Saúde, Azinhaga de Santa Comba, 3000-548 Coimbra, Portugal.
Nuno R FerreiraDepartment of Pharmaceutical Technology, Faculty of Pharmacy, University of Coimbra (FFUC), Pólo das Ciências da Saúde, Azinhaga de Santa Comba, 3000-548 Coimbra, Portugal.ORCID 0000-0001-9587-682X
Alessandra DurazzoCREA-Research Centre for Food and Nutrition, Via Ardeatina 546, 00178 Rome, Italy.ORCID 0000-0002-7747-9107
Massimo LucariniCREA-Research Centre for Food and Nutrition, Via Ardeatina 546, 00178 Rome, Italy.
Nicola CiceroDipartimento di Scienze biomediche, odontoiatriche e delle immagini morfologiche e funzionali, Università degli Studi di Messina, Polo Universitario Annunziata, 98168 Messina, Italy.ORCID 0000-0002-8055-1915
Soukaina El MamouniDepartment of Pharmacy, University of Napoli Federico II, 80138 Napoli NA, Italy.
Amélia M SilvaDepartment of Biology and Environment, University of Trás-os-Montes e Alto Douro (UTAD), Quinta de Prados, P-5001-801 Vila Real, Portugal.ORCID 0000-0002-7524-9914
Izabela NowakFaculty of Chemistry, Adam Mickiewicz University in Poznań, 61-712 Poznań, Poland.ORCID 0000-0002-1113-9011
Antonello SantiniDepartment of Pharmacy, University of Napoli Federico II, 80138 Napoli NA, Italy. asantini@unina.it.
Eliana B SoutoDepartment of Pharmaceutical Technology, Faculty of Pharmacy, University of Coimbra (FFUC), Pólo das Ciências da Saúde, Azinhaga de Santa Comba, 3000-548 Coimbra, Portugal. ebsouto@ebsouto.pt.ORCID 0000-0001-5505-3327

Funding

Portuguese Science and Technology Foundation (FCT/MCT) and European Funds (PRODER/COMPETE) co-financed by FEDER, under the Partnership Agreement PT2020 M-ERA-NET/0004/2015-PAIRED
6 · The paper itself

Abstract

The encapsulation of bicyclic monoterpene α-pinene into solid lipid nanoparticles (SLN) is reported using experimental factorial design, followed by high-end dispersion analyzer LUMiSizer

Indexed as

Bicyclic MonoterpenesChemical PhenomenaLipidsMolecular StructureNanoparticlesParticle SizePoloxamerSurface-Active Agentsalpha-pineneBicyclic MonoterpenesLipidsPoloxamerSurface-Active Agentsdispersion analyzerfactorial designinstability phenomenaoptimizationsolid lipid nanoparticlesα-pinene

Identifiers

PMID31344802
PMCPMC6696006

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.